Gene Symbol | TUSC2 |
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Entrez Gene | 11334 |
Alt Symbol | C3orf11, FUS1, PAP, PDAP2 |
Species | Human |
Gene Type | protein-coding |
Description | tumor suppressor candidate 2 |
Other Description | PDGFA associated protein 2|PDGFA-associated protein 2|fus-1 protein|fusion 1 protein |
Swissprots | O75896 B2R4Y9 |
Accessions | EAW65095 EAW65096 EAW65097 O75896 AF055479 AAC35497 AK124058 AK311998 BAG34936 BC023976 AAH23976 CA392689 HQ448135 ADQ32616 NM_007275 NP_009206 |
Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
Tissue Specificity | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |
TUSC2 CRISPR/Cas9 KO Plasmid (h) - sc-407062 from Santa Cruz Biotechnology
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TUSC2 HDR Plasmid (h) - sc-407062-HDR from Santa Cruz Biotechnology
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TUSC2 Double Nickase Plasmid (h) - sc-407062-NIC from Santa Cruz Biotechnology
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TUSC2 Double Nickase Plasmid (h2) - sc-407062-NIC-2 from Santa Cruz Biotechnology
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TUSC2 CRISPR Activation Plasmid (h) - sc-407062-ACT from Santa Cruz Biotechnology
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TUSC2 CRISPR Activation Plasmid (h2) - sc-407062-ACT-2 from Santa Cruz Biotechnology
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TUSC2 Lentiviral Activation Particles (h) - sc-407062-LAC from Santa Cruz Biotechnology
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TUSC2 Lentiviral Activation Particles (h2) - sc-407062-LAC-2 from Santa Cruz Biotechnology
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TUSC2 siRNA (h) - sc-77910 from Santa Cruz Biotechnology
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TUSC2 shRNA Plasmid (h) - sc-77910-SH from Santa Cruz Biotechnology
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TUSC2 shRNA (h) Lentiviral Particles - sc-77910-V from Santa Cruz Biotechnology
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TUSC2 RNAi - H00011334-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN22287 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22287 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08751 from Sigma-Aldrich
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TUSC2 siRNA (Human) - CRH7761 from Cohesion Biosciences
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TUSC2 - MBS828644 from MyBioSource
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TUSC2 CRISPR/Cas9 KO Plasmid (h2) - sc-407062-KO-2 from Santa Cruz Biotechnology
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TUSC2 HDR Plasmid (h2) - sc-407062-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TUSC2 (NM_007275.1) - SHH437984 from Creative biogene
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shRNA set against Human TUSC2(NM_007275.1) - SHL107134 from Creative biogene
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Human TUSC2 siRNA - orb268263 from Biorbyt
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TUSC2 shRNA Plasmid (Human) - CHH7761 from Cohesion Biosciences
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TUSC2 miRNA 3'UTR clone - MiUTR1H-10885 from Creative biogene
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