Gene Symbol | TUSC2 |
---|---|
Entrez Gene | 11334 |
Alt Symbol | C3orf11, FUS1, PAP, PDAP2 |
Species | Human |
Gene Type | protein-coding |
Description | tumor suppressor candidate 2 |
Other Description | PDGFA associated protein 2|PDGFA-associated protein 2|fus-1 protein|fusion 1 protein |
Swissprots | O75896 B2R4Y9 |
Accessions | EAW65095 EAW65096 EAW65097 O75896 AF055479 AAC35497 AK124058 AK311998 BAG34936 BC023976 AAH23976 CA392689 HQ448135 ADQ32616 NM_007275 NP_009206 |
Function | May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. |
Tissue Specificity | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |