CLIC1

Gene Symbol	CLIC1
Entrez Gene	1192
Alt Symbol	G6, NCC27
Species	Human
Gene Type	protein-coding
Description	chloride intracellular channel 1
Other Description	RNCC protein|chloride channel ABP|chloride intracellular channel protein 1|hRNCC|nuclear chloride ion channel 27|nuclear chloride ion channel protein|p64CLCP|regulatory nuclear chloride ion channel protein
Swissprots	O00299 Q502X1 Q15089
Accessions	AAD18073 BAB63376 CAB46078 EAX03503 EAX03504 EAX03505 O00299 AF034607 AAD20437 AF109197 AAD26137 AI192421 AK129773 AK223379 BAD97099 AK314014 BAG36725 BC064527 AAH64527 BC095469 AAH95469 BM562536 CB124154 CR542071 CAG46868 CX783058 HY057217 U93205 AAC25675 X87689 CAA61020 NM_001287593 NP_001274522 NM_001287594 NP_001274523 NM_001288 NP_001279
Function	Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. {ECO:0000269|PubMed:10834939, ECO:0000269|PubMed:11195932, ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:11940526, ECO:0000269|PubMed:11978800, ECO:0000269|PubMed:14613939, ECO:0000269|PubMed:9139710}.
Subcellular Location	Nucleus. Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm. Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Tissue Specificity	Expression is prominent in heart, placenta, liver, kidney and pancreas. {ECO:0000269|PubMed:10793131}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CLIC1 full length protein - ab172845 from Abcam Category Protein Source E. coli Species Human

Human CLIC1 full length protein - ab95486 from Abcam Category Protein Source E. coli Species Human

Human CLIC1 full length protein - ab119166 from Abcam Category Protein Source E. coli Species Human

CLIC1 / NCC27 Antibody Blocking Peptide - LS-E9079 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLIC1 / NCC27 Antibody Blocking Peptide - LS-E12479 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLIC1 Recombinant Protein - H00001192-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CLIC1 Protein - NBP1-44454 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E. coli Species Human

CLIC1-Antibody-Blocking-Peptide - BP7589a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLIC1 Protein (OPPA02273) - OPPA02273 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human hRNCC protein - orb138579 from Biorbyt Category Protein Prices $298.00, $612.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human NCC27 protein - orb163533 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

CLIC1 Blocking Peptide - 33R-5478 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CLIC1 Blocking Peptide - 33R-3502 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CLIC1 protein (His tag) - 80R-1332 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

CLIC1 (1-241, His-tag) - AR09478PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

CLIC1 (1-241, His-tag) - AR09478PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

CLIC1 - H00001192-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CLIC1 - H00001192-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Chloride Intracellular Channel 1, Human Recombinant - 228-13274-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Chloride Intracellular Channel 1 - 228-13274-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Chloride Intracellular Channel 1 - 228-13274-3 from RayBiotech Category Protein Prices $2,400.00 Sizes 3 µg Source Escherichia Coli. Species Human

CLIC1, 1-241aa, Human, His tag, E.coli - 01-1838-1 from ARP American Research Products Category Protein Prices $159.00, $339.00, $749.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CLIC1, Human, Recombinant - 19-CG13 from ARP American Research Products Category Protein Prices $119.00 Sizes 10 µg Source E. coli Species Human

CLIC1 fusion protein - Ag6049 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CLIC1 Protein - BP001882-CG13 from Syd Labs Category Protein Prices $98.00, $300.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

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