CLIC1

Gene Symbol CLIC1
Entrez Gene 1192
Alt Symbol G6, NCC27
Species Human
Gene Type protein-coding
Description chloride intracellular channel 1
Other Description RNCC protein|chloride channel ABP|chloride intracellular channel protein 1|hRNCC|nuclear chloride ion channel 27|nuclear chloride ion channel protein|p64CLCP|regulatory nuclear chloride ion channel protein
Swissprots O00299 Q502X1 Q15089
Accessions AAD18073 BAB63376 CAB46078 EAX03503 EAX03504 EAX03505 O00299 AF034607 AAD20437 AF109197 AAD26137 AI192421 AK129773 AK223379 BAD97099 AK314014 BAG36725 BC064527 AAH64527 BC095469 AAH95469 BM562536 CB124154 CR542071 CAG46868 CX783058 HY057217 U93205 AAC25675 X87689 CAA61020 NM_001287593 NP_001274522 NM_001287594 NP_001274523 NM_001288 NP_001279
Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. {ECO:0000269|PubMed:10834939, ECO:0000269|PubMed:11195932, ECO:0000269|PubMed:11551966, ECO:0000269|PubMed:11940526, ECO:0000269|PubMed:11978800, ECO:0000269|PubMed:14613939, ECO:0000269|PubMed:9139710}.
Subcellular Location Nucleus. Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm. Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Tissue Specificity Expression is prominent in heart, placenta, liver, kidney and pancreas. {ECO:0000269|PubMed:10793131}.

CLIC1 CRISPR/Cas9 KO Plasmid (h) - sc-402391 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 HDR Plasmid (h) - sc-402391-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 Double Nickase Plasmid (h) - sc-402391-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 Double Nickase Plasmid (h2) - sc-402391-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 CRISPR Activation Plasmid (h) - sc-402391-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 CRISPR Activation Plasmid (h2) - sc-402391-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 Lentiviral Activation Particles (h) - sc-402391-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 Lentiviral Activation Particles (h2) - sc-402391-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLIC1 siRNA (h) - sc-60400 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLIC1 shRNA Plasmid (h) - sc-60400-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLIC1 shRNA (h) Lentiviral Particles - sc-60400-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLIC1 RNAi - H00001192-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU106371 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6228 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6228 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLIC1 siRNA (Human) - CRH0852 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLIC1 - MBS8201416 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLIC1 (NM_001288.4) - SHH265277 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CLIC1(NM_001288.4) - SHG182537 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLIC1 siRNA - orb261354 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLIC1 shRNA Plasmid (Human) - CHH0852 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLIC1 miRNA 3'UTR clone - MiUTR1H-02220 from Creative biogene

Species Reactivities Human
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