NSD1

Gene Symbol NSD1
Entrez Gene 64324
Alt Symbol ARA267, KMT3B, SOTOS, SOTOS1, STO
Species Human
Gene Type protein-coding
Description nuclear receptor binding SET domain protein 1
Other Description H3-K36-HMTase|H4-K20-HMTase|NR-binding SET domain-containing protein|androgen receptor coactivator 267 kDa protein|androgen receptor-associated coregulator 267|androgen receptor-associated protein of 267 kDa|histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific|lysine N-methyltransferase 3B|nuclear receptor-binding SET domain-containing protein 1
Swissprots Q96RN7 Q96PD8 Q96L73
Accessions CCO13784 EAW85031 EAW85032 EAW85033 Q96L73 AF085858 AF322907 AAK92049 AF380302 AAL27991 AF395588 AAL40694 AK001546 AK025916 BAB15281 AK026066 BAB15346 AK055187 BAB70868 AK056667 BAB71247 AK091358 BAC03645 AK126591 AL832983 CAH56331 AY049721 AAL06645 BC021961 AAH21961 BC139789 AAI39790 BC144629 BC150628 AAI50629 CK300021 CN333750 XM_005265959 XP_005266016 XM_005265960 XP_005266017 XM_005265961 XP_005266018 XM_005265962 XP_005266019 XM_011534610 XP_011532912 XM_011534611 XP_011532913 XM_011534612 XP_011532914 XM_011534613 XP_011532915 XM_011534614 XP_011532916 XM_011534615 XP_011532917 XM_011534616 XP_011532918 XM_011534617 XP_011532919 NM_022455 NP_071900 NM_172349 NP_758859
Function Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. {ECO:0000269|PubMed:21196496}.
Subcellular Location Nucleus. Chromosome {ECO:0000305}.
Tissue Specificity Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung.
Top Pathways Lysine degradation

NSD1 (C-15) - sc-46016 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NSD1 (D-20) - sc-32479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NSD1 (N-15) - sc-46018 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NSD1 (N-20) - sc-32475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NSD1 (K47) - sc-130470 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
NSD1 (K47): sc-130470. Western blot analysis of NSD1 expression in human uterus tissue extract.

Anti-KMT3B / NSD1 antibody - ab89432 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-KMT3B / NSD1 antibody (ab89432) at 1 µg/ml + KMT3B / NSD1 partial recombinant protein at 0.2 µg

Anti-KMT3B / NSD1 antibody - ab84137 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84137, at a 1/250 dilution, staining KMT3B / NSD1 in formalin fixed, paraffin embedded human prostate adenocarcinoma by Immunohistochemistry. Detection: DAB

Anti-KMT3B / NSD1 antibody [2658C1a] - ab70732 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2658C1a
Anti-KMT3B / NSD1 antibody [2658C1a] (ab70732) + immunising recombinant protein

Anti-NSD1 Antibody (clone 2658C1a) - LS-C342683 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2658C1a
Western blot analysis of immunized recombinant protein, using anti-NSD1 monoclonal antibody.

Anti-NSD1 Antibody (aa650-700) - LS-C286303 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human NSD1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-NSD1 used at a dilution of 1:250.

Anti-NSD1 Antibody (aa650-700) - LS-C73730 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NSD1 Antibody - LS-C73731 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-NSD1 Antibody (clone 4F1) - LS-C139162 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F1

Anti-NSD1 Antibody (clone 3E6) - LS-C139536 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E6

Anti-NSD1 Antibody (clone 2658C1a) - LS-C184648 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2658C1a

Anti-NSD1 Antibody - LS-C178312 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
NSD1-M antibody at 1/1000 dilution + HepG2 whole cell lysate.

Anti-NSD1 Antibody (aa2-110, Azide-free) - LS-C328059 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

KMT3B/NSD1 Antibody - NB100-1744 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: KMT3B/NSD1 Antibody [NB100-1744] - Sample : FFPE section of human prostate adenocarcinoma. Antibody : Affinity purified rabbit anti-NSD1 used at a dilution of 1:250. Detection : DAB

KMT3B/NSD1 Antibody (4F1) - H00064324-M08 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F1
Western Blot: KMT3B/NSD1 Antibody (4F1) [H00064324-M08] - NSD1 monoclonal antibody (M08), clone 4F1. Western Blot analysis of NSD1 expression in human uterus myoma.

KMT3B/NSD1 Antibody - H00064324-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

KMT3B/NSD1 Antibody (1C12) - H00064324-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C12

NSD1 Polyclonal Antibody - bs-8170R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-NSD1 Polyclonal Antibody, Unconjugated (bs-8170R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Monoclonal Anti-NSD1 antibody produced in mouse - WH0064324M5 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C12
<B>Immunoblotting</B><BR/>Monoclonal Anti-NSD1, <B>Cat. No. WH0064324M5</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.99 kDa using immunogen protein lysate.

Monoclonal Anti-NSD1 antibody produced in mouse - SAB1405251 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F1
<B>Immunoblotting</B><BR/>Monoclonal Anti-NSD1: <B>Cat. No. SAB1405251</B>: Antibody concentration: 1 μg/mL. Specific band of ~38 kDa using immunogen protein lysate.

NSD1-Antibody-monoclonal-M08 - AT3117a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F1
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.62 KDa) .
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