NSD1

Gene Symbol NSD1
Entrez Gene 64324
Alt Symbol ARA267, KMT3B, SOTOS, SOTOS1, STO
Species Human
Gene Type protein-coding
Description nuclear receptor binding SET domain protein 1
Other Description H3-K36-HMTase|H4-K20-HMTase|NR-binding SET domain-containing protein|androgen receptor coactivator 267 kDa protein|androgen receptor-associated coregulator 267|androgen receptor-associated protein of 267 kDa|histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific|lysine N-methyltransferase 3B|nuclear receptor-binding SET domain-containing protein 1
Swissprots Q96RN7 Q96PD8 Q96L73
Accessions CCO13784 EAW85031 EAW85032 EAW85033 Q96L73 AF085858 AF322907 AAK92049 AF380302 AAL27991 AF395588 AAL40694 AK001546 AK025916 BAB15281 AK026066 BAB15346 AK055187 BAB70868 AK056667 BAB71247 AK091358 BAC03645 AK126591 AL832983 CAH56331 AY049721 AAL06645 BC021961 AAH21961 BC139789 AAI39790 BC144629 BC150628 AAI50629 CK300021 CN333750 XM_005265959 XP_005266016 XM_005265960 XP_005266017 XM_005265961 XP_005266018 XM_005265962 XP_005266019 XM_011534610 XP_011532912 XM_011534611 XP_011532913 XM_011534612 XP_011532914 XM_011534613 XP_011532915 XM_011534614 XP_011532916 XM_011534615 XP_011532917 XM_011534616 XP_011532918 XM_011534617 XP_011532919 NM_022455 NP_071900 NM_172349 NP_758859
Function Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. {ECO:0000269|PubMed:21196496}.
Subcellular Location Nucleus. Chromosome {ECO:0000305}.
Tissue Specificity Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung.
Top Pathways Lysine degradation

NSD1 CRISPR/Cas9 KO Plasmid (h) - sc-401541 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 HDR Plasmid (h) - sc-401541-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 Double Nickase Plasmid (h) - sc-401541-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 Double Nickase Plasmid (h2) - sc-401541-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 CRISPR Activation Plasmid (h) - sc-401541-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 CRISPR Activation Plasmid (h2) - sc-401541-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 Lentiviral Activation Particles (h) - sc-401541-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 Lentiviral Activation Particles (h2) - sc-401541-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NSD1 siRNA (h) - sc-45612 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NSD1 shRNA Plasmid (h) - sc-45612-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NSD1 shRNA (h) Lentiviral Particles - sc-45612-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KMT3B/NSD1 RNAi - H00064324-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KMT3B/NSD1 RNAi - H00064324-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU081541 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1510 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1510 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NSD1 siRNA (Human) - CRJ1984 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NSD1 (NM_022455.4) - SHH355308 from Creative biogene

Category siRNA
Species Reactivities Human

Human NSD1 siRNA - orb272485 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NSD1 shRNA Plasmid (Human) - CHJ1984 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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