NSD1

Gene Symbol	NSD1
Entrez Gene	64324
Alt Symbol	ARA267, KMT3B, SOTOS, SOTOS1, STO
Species	Human
Gene Type	protein-coding
Description	nuclear receptor binding SET domain protein 1
Other Description	H3-K36-HMTase|H4-K20-HMTase|NR-binding SET domain-containing protein|androgen receptor coactivator 267 kDa protein|androgen receptor-associated coregulator 267|androgen receptor-associated protein of 267 kDa|histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific|lysine N-methyltransferase 3B|nuclear receptor-binding SET domain-containing protein 1
Swissprots	Q96RN7 Q96PD8 Q96L73
Accessions	CCO13784 EAW85031 EAW85032 EAW85033 Q96L73 AF085858 AF322907 AAK92049 AF380302 AAL27991 AF395588 AAL40694 AK001546 AK025916 BAB15281 AK026066 BAB15346 AK055187 BAB70868 AK056667 BAB71247 AK091358 BAC03645 AK126591 AL832983 CAH56331 AY049721 AAL06645 BC021961 AAH21961 BC139789 AAI39790 BC144629 BC150628 AAI50629 CK300021 CN333750 XM_005265959 XP_005266016 XM_005265960 XP_005266017 XM_005265961 XP_005266018 XM_005265962 XP_005266019 XM_011534610 XP_011532912 XM_011534611 XP_011532913 XM_011534612 XP_011532914 XM_011534613 XP_011532915 XM_011534614 XP_011532916 XM_011534615 XP_011532917 XM_011534616 XP_011532918 XM_011534617 XP_011532919 NM_022455 NP_071900 NM_172349 NP_758859
Function	Histone methyltransferase. Preferentially methylates 'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context. {ECO:0000269|PubMed:21196496}.
Subcellular Location	Nucleus. Chromosome {ECO:0000305}.
Tissue Specificity	Expressed in the fetal/adult brain, kidney, skeletal muscle, spleen, and the thymus, and faintly in the lung.
Top Pathways	Lysine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human KMT3B / NSD1 protein fragment - ab196419 from Abcam Category Protein Prices $858.00 Sizes 50 µg Source E. coli Species Human

Human KMT3B / NSD1 protein fragment - ab163817 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human KMT3B/NSD1 Protein - H00064324-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NSD1 - H00064324-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NSD1 - H00064324-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant NSD1-SET protein - 31475 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 50 µg, 1 mg Source E. coli Species Human

Recombinant Human NSD1, GST-tagged - NSD1-82H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific(NSD1) ,partial - CSB-YP856971HU CSB-EP856971HU CSB-BP856971HU CSB-MP856971HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human NSD1 Protein, His-tagged - NSD1-143H from Creative Biomart Category Protein Source Insect cell Species Human

NSD1 Peptide, Human - M34GP10641H from Creative Peptides Category Peptide Source Synthetic. Species Human

KMT3B/NSD1 Recombinant Protein Antigen - NBP2-56325PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KMT3B/NSD1 Recombinant Protein Antigen - NBP2-55512PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (NSD1), partial, Recombinant Protein - MBS1366712 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

NSD1 fusion protein - Ag26432 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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