APLNR

Gene Symbol APLNR
Entrez Gene 187
Alt Symbol AGTRL1, APJ, APJR, HG11
Species Human
Gene Type protein-coding
Description apelin receptor
Other Description APJ (apelin) receptor|APJ receptor|G protein-coupled receptor APJ|G-protein coupled receptor APJ|G-protein coupled receptor HG11|HG11 orphan receptor|angiotensin II receptor-like 1|angiotensin receptor-like 1
Swissprots P35414
Accessions AAA18954 EAW73730 P35414 AK074514 BAC11032 AK075252 BAG52096 AK097232 BAG53437 AK315542 BAG37920 AL548962 AL553350 BC032688 AAH32688 BI004477 BM698661 BX439288 DQ890844 ABM81770 EU176506 ABW03307 X89271 CAA61546 NM_005161 NP_005152 NR_027991
Function Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.
Top Pathways Neuroactive ligand-receptor interaction

APLNR CRISPR/Cas9 KO Plasmid (h) - sc-402374 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR HDR Plasmid (h) - sc-402374-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR Double Nickase Plasmid (h) - sc-402374-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR Double Nickase Plasmid (h2) - sc-402374-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR CRISPR Activation Plasmid (h) - sc-402374-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR CRISPR Activation Plasmid (h2) - sc-402374-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR Lentiviral Activation Particles (h) - sc-402374-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR Lentiviral Activation Particles (h2) - sc-402374-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APLNR siRNA (h) - sc-44732 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APLNR shRNA Plasmid (h) - sc-44732-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APLNR shRNA (h) Lentiviral Particles - sc-44732-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APJ/Apelin receptor RNAi - H00000187-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU132881 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3324 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11148 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11148

APLNR siRNA (Human) - CRH0132 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APLNR - MBS8220311 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APLNR (NM_005161.4) - SHH238282 from Creative biogene

Category siRNA
Species Reactivities Human

APLNR shRNA Plasmid (Human) - CHH0132 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APLNR miRNA 3'UTR clone - MiUTR4H-TG00408 from Creative biogene

Species Reactivities Human
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