SLC12A5

Gene Symbol SLC12A5
Entrez Gene 57468
Alt Symbol KCC2
Species Human
Gene Type protein-coding
Description solute carrier family 12 (potassium/chloride transporter), member 5
Other Description K-Cl cotransporter 2|electroneutral potassium-chloride cotransporter 2|erythroid K-Cl cotransporter 2|hKCC2|neuronal K-Cl cotransporter|solute carrier family 12 member 5
Swissprots Q9H4Z0 Q9H2X9 Q5VZ41 A2RTX2 Q9ULP4
Accessions EAW75771 EAW75772 EAW75773 Q9H2X9 AB033002 BAA86490 AF208159 AAG43493 AK055066 AK098371 AK289758 BAF82447 AK294059 BAH11662 AK295096 BAH11972 AK295900 BAH12216 AK296331 BAH12319 BC036329 BC132668 AAI32669 BC132670 AAI32671 DA102113 DC320473 KC295693 AGH06150 KC295694 AGH06151 KC295695 AGH06152 KC295696 AGH06153 KC295697 AGH06154 KC295698 AGH06155 KC295699 AGH06156 KC295700 AGH06157 KC295701 AGH06158 U79245 NM_001134771 NP_001128243 NM_020708 NP_065759
Function Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Brain specific. Detected in neuronal cells.
Top Pathways GABAergic synapse

KCC2 CRISPR/Cas9 KO Plasmid (h) - sc-402080 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 HDR Plasmid (h) - sc-402080-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 Double Nickase Plasmid (h) - sc-402080-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 Double Nickase Plasmid (h2) - sc-402080-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 CRISPR Activation Plasmid (h) - sc-402080-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 CRISPR Activation Plasmid (h2) - sc-402080-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 Lentiviral Activation Particles (h) - sc-402080-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 Lentiviral Activation Particles (h2) - sc-402080-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 siRNA (h) - sc-42606 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC2 shRNA Plasmid (h) - sc-42606-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC2 shRNA (h) Lentiviral Particles - sc-42606-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KCC2/SLC12A5 RNAi - H00057468-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU006121 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19407 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19407 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11556 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11556

SLC12A5 siRNA (Human) - CRJ1461 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC12A5 - MBS8216172 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCC2 CRISPR/Cas9 KO Plasmid (h2) - sc-402080-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KCC2 HDR Plasmid (h2) - sc-402080-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human SLC12A5 siRNA - orb271962 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC12A5 shRNA Plasmid (Human) - CHJ1461 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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