Gene Symbol | PRG3 |
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Entrez Gene | 10394 |
Alt Symbol | MBP2, MBPH |
Species | Human |
Gene Type | protein-coding |
Description | proteoglycan 3 |
Other Description | eosinophil major basic protein homolog|prepro-MBPH|prepro-major basic protein homolog |
Swissprots | Q9Y2Y8 |
Accessions | AAG41952 EAW73738 Q9Y2Y8 AF132209 AAD24471 AY358930 AAQ89289 BC069126 AAH69126 BC101613 AAI01614 BC113411 AAI13412 HQ258112 ADR82866 NM_006093 NP_006084 |
Function | Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils. {ECO:0000269|PubMed:10318872}. |
Subcellular Location | Cytoplasmic granule {ECO:0000269|PubMed:10318872}. Note=Localized to the eosinophil secondary granule. |
Tissue Specificity | Expressed in bone marrow. Not detected in placenta. {ECO:0000269|PubMed:10318872}. |
MBPH (N-17) - sc-109320 from Santa Cruz Biotechnology
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MBPH (E-12) - sc-109318 from Santa Cruz Biotechnology
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Anti-PRG3 antibody - ab201156 from Abcam
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Anti-PRG3 antibody [EPR13990] - ab182142 from Abcam
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Anti-PRG3 Antibody (aa170-185) - LS-C87106 from LifeSpan Bioscience
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Anti-PRG3 Antibody - LS-C152803 from LifeSpan Bioscience
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PRG3 Antibody - NBP2-38047 from Novus Biologicals
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PRG3 Antibody - C-terminal region (ARP75352_P050) - ARP75352_P050 from Aviva Systems Biology
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PRG3 antibody - 70R-PR053 from Fitzgerald
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Proteoglycan 3 antibody - H00010394-B01P from Acris Antibodies
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Proteoglycan 3 antibody - PAB1066 from Acris Antibodies
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PRG3 antibody - 18069-1-AP from Proteintech Group
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Anti- Proteoglycan 3 (PRG3) Antibody - GWB-59B5DC from Genway Biotech
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Anti-PRG3 (aa 170-185) polyclonal antibody - DPAB-DC201 from Creative Diagnostics
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PRG3, Polyclonal Antibody - MBS535224 from MyBioSource
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PRG3 antibody - pab50137 from Covalab
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PRG3 Antibody - abx122618 from Abbexa
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Anti-PRG3 antibody produced in rabbit - HPA064183 from Sigma-Aldrich
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PRG3 antibody - orb258664 from Biorbyt
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PRG3 Antibody - 42923 from Signalway Antibody
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Proteoglycan 3 antibody - TA309569 from Acris Antibodies
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Afuco™ Anti-Human PRG3 ADCC Theraputic Antibody, ADCC Enhanced - AFC-708CL from Creative Biolabs |
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Anti-Human PRG3 Therapeutic Antibody (4F1) - TAB-1060CL from Creative Biolabs
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Anti-Human PRG3 Therapeutic Antibody Fab Fragment (4F1) - TAB-1060CL-F(E) from Creative Biolabs
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Anti-Human PRG3 Therapeutic Antibody scFv Fragment (4F1) - TAB-1060CL-S(P) from Creative Biolabs
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