TMED2

Gene Symbol	TMED2
Entrez Gene	10959
Alt Symbol	P24A, RNP24, p24
Species	Human
Gene Type	protein-coding
Description	transmembrane emp24 domain trafficking protein 2
Other Description	coated vesicle membrane protein|membrane protein p24A|p24 family protein beta-1|p24beta1|transmembrane emp24 domain-containing protein 2
Swissprots	Q15363
Accessions	EAW98417 EAW98418 Q15363 AK024976 AK298167 BAG60439 AK303189 BAG64282 AK312975 BAG35812 BC025957 AAH25957 BI086507 CR541663 CAG46464 CR541682 CAG46483 X92098 CAA63069 XM_005253544 XP_005253601 NM_006815 NP_006806
Function	Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase- activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Gol
Subcellular Location	Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Cycles between compartments of the early secretatory pathway.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TMED2 (A-8) - sc-376033 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

TMED2 (C-8) - sc-376459 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

TMED2 (H-108) - sc-292002 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

TMED2 (E-12) - sc-376458 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Anti-TMED2 antibody - ab97600 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 antibody - ab129412 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, APC) - LS-C271660 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, AP) - LS-C271659 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, Biotin) - LS-C271661 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, FITC) - LS-C271663 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, PE) - LS-C271666 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79, Azide-free, HRP) - LS-C271664 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa49-79) - LS-C325783 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa95-144) - LS-C152219 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa50-79) - LS-C161954 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 Antibody (aa9-201) - LS-C186404 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TMED2 Antibody - NBP1-80963 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-TMED2 antibody produced in rabbit - SAB2700521 from Sigma-Aldrich Prices $326.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-TMED2 (N-TERM) antibody produced in rabbit - SAB1303568 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TMED2 antibody produced in rabbit - HPA014060 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TMED2 Antibody - middle region (ARP66706_P050) - ARP66706_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TMED2-Antibody-N-term - AP13140a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

TMED2 Antibody - N-terminal region (OAAB09439) - OAAB09439 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

TMED2 antibody - orb74231 from Biorbyt Prices $723.00 Sizes 100 μl Host Rabbit Clonality Polyclonal

HIV1 p24 antibody - 10-H30N from Fitzgerald Prices $225.00 Sizes 200 µg Host Mouse Clonality Monoclonal Clone M106161

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