PC

Gene Symbol PC
Entrez Gene 5091
Alt Symbol PCB
Species Human
Gene Type protein-coding
Description pyruvate carboxylase
Other Description pyruvate carboxylase, mitochondrial|pyruvic carboxylase
Swissprots P11498 B4DN00 Q16705
Accessions CBF60260 CBF61085 CBF62141 CBF64322 CBF68536 CBF95786 CBU85504 CBU86113 CBU87017 CBU89198 CBU93410 CBV09306 EAW74568 EAW74569 EAW74570 EAW74571 EAW74572 P11498 AK297705 BAG60062 BC011617 AAH11617 CN267865 DA542083 K02282 AAA60033 M26122 AAA36423 S72370 AAB31500 U04641 AAA99537 U30889 U30890 U30891 AAA82937 XM_005274031 XP_005274088 XM_005274032 XP_005274089 XM_006718577 XP_006718640 XM_006718578 XP_006718641 XM_006718579 XP_006718642 XM_011545085 XP_011543387 XM_011545086 XP_011543388 XM_011545087 XP_011543389 XM_011545088 XP_011543390 NM_000920 NP_000911 NM_001040716 NP_001035806 NM_022172 NP_071504
Function Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
Subcellular Location Mitochondrion matrix.
Top Pathways Citrate cycle (TCA cycle), Pyruvate metabolism, Biosynthesis of amino acids, Carbon metabolism

PCB (N-12) - sc-46230 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCB (N-12): sc-46230. Western blot analysis of PCB expression in mouse liver (A) and rat kidney (B) tissue extracts.

PCB (H-2) - sc-271493 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (H-2): sc-271493. Western blot analysis of PCB expression in 293T whole cell lysate.

PCB (B-6) - sc-271862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (B-6): sc-271862. Western blot analysis of PCB expression in mouse liver tissue extract.

PCB (H-300) - sc-67021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PCB (H-300): sc-67021. Western blot analysis of PCB expression in mouse brain tissue extract.

PCB (F-3) - sc-365491 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (F-3): sc-365491. Western blot analysis of PCB expression in non-transfected: sc-117752 (A) and mouse PCB transfected: sc-122419 (B) 293T whole cell lysates.

PCB (E-5) - sc-365672 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (E-5): sc-365672. Western blot analysis of PCB expression in non-transfected: sc-117752 (A) and mouse PCB transfected: sc-122419 (B) 293T whole cell lysates.

PCB (C-15) - sc-46229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCB (C-15): sc-46229. Western blot analysis of PCB expression in mouse liver (A), rat kidney (B) and mouse brain (C) tissue extracts.

PCB (D-9) - sc-365673 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (D-9): sc-365673. Western blot analysis of PCB expression in non-transfected: sc-117752 (A) and mouse PCB transfected: sc-122419 (B) 293T whole cell lysates.

PCB (E-1) - sc-373937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PCB (E-1): sc-373937. Western blot analysis of PCB expression in non-transfected: sc-117752 (A) and mouse PCB transfected: sc-122419 (B) 293T whole cell lysates.

PCB (N-16) - sc-46231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCB (N-16): sc-46231. Immunoperoxidase staining of formalin fixed, paraffin-embedded human seminal vesicle tissue showing cytoplasmic staining of glandular cells.

PCB (C-13) - sc-46228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PCB (C-13): sc-46228. Western blot analysis of PCB expression in mouse liver (A) and rat kidney (B) tissue extracts.

Anti-PCB antibody - ab182787 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PCB antibody (ab182787) at 1/200 dilution + HeLa cell lysate at 40 µgSecondaryGoat anti Rabbit IgG at 1/10000 dilution

Anti-PCB antibody - ab113020 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PCB antibody (ab113020) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

Anti-PCB antibody - ab137942 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PCB antibody (ab137942) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-PCB antibody [10G7BF7] - ab123451 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10G7BF7
All lanes : Anti-PCB antibody [10G7BF7] (ab123451) at 1 µg/mlLane 1 : HepG2 cell lysateLane 2 : HelaLane 3 : H9C2Lane 4 : MEFLane 5 : Recombinant PCLysates/proteins at 15 µg per lane.SecondaryGoat-anti-Mouse HRP at 1/3000 dilution

Anti-PCB antibody [EPR7365] - ab128952 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7365
All lanes : Anti-PCB antibody [EPR7365] (ab128952) at 1/1000 dilutionLane 1 : fetal liver lysateLane 2 : fetal kidney lysateLane 3 : HepG2 lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PCB antibody [EPR7366] - ab126707 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7366
All lanes : Anti-PCB antibody [EPR7366] (ab126707) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : HepG2 lysateLane 3 : Human fetal liver lysateLane 4 : A549 lysateLysates/proteins at 10 µg per lane.

Anti-PC / Pyruvate Carboxylase Antibody (aa53-82, FITC) - LS-C265730 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PC / Pyruvate Carboxylase Antibody (aa53-82, APC) - LS-C265731 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PC / Pyruvate Carboxylase Antibody (aa341-390) - LS-C200468 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HT-29 cells using PC antibody.

Anti-PC / Pyruvate Carboxylase Antibody (Internal, clone EPR7366) - LS-C152355 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7366
Western blot analysis on (A) mouse brain and (B) rat brain lysates using anti-Pyruvate Carboxylase antibody.

Anti-PC / Pyruvate Carboxylase Antibody (aa53-82, AP) - LS-C265732 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PC / Pyruvate Carboxylase Antibody - LS-C285798 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PC / Pyruvate Carboxylase Antibody (aa53-82, PE) - LS-C265734 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PC / Pyruvate Carboxylase Antibody (FITC) - LS-C317361 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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