PC

Gene Symbol PC
Entrez Gene 5091
Alt Symbol PCB
Species Human
Gene Type protein-coding
Description pyruvate carboxylase
Other Description pyruvate carboxylase, mitochondrial|pyruvic carboxylase
Swissprots P11498 B4DN00 Q16705
Accessions CBF60260 CBF61085 CBF62141 CBF64322 CBF68536 CBF95786 CBU85504 CBU86113 CBU87017 CBU89198 CBU93410 CBV09306 EAW74568 EAW74569 EAW74570 EAW74571 EAW74572 P11498 AK297705 BAG60062 BC011617 AAH11617 CN267865 DA542083 K02282 AAA60033 M26122 AAA36423 S72370 AAB31500 U04641 AAA99537 U30889 U30890 U30891 AAA82937 XM_005274031 XP_005274088 XM_005274032 XP_005274089 XM_006718577 XP_006718640 XM_006718578 XP_006718641 XM_006718579 XP_006718642 XM_011545085 XP_011543387 XM_011545086 XP_011543388 XM_011545087 XP_011543389 XM_011545088 XP_011543390 NM_000920 NP_000911 NM_001040716 NP_001035806 NM_022172 NP_071504
Function Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
Subcellular Location Mitochondrion matrix.
Top Pathways Citrate cycle (TCA cycle), Pyruvate metabolism, Biosynthesis of amino acids, Carbon metabolism

PCB CRISPR/Cas9 KO Plasmid (h) - sc-401254 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB HDR Plasmid (h) - sc-401254-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB Double Nickase Plasmid (h) - sc-401254-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB Double Nickase Plasmid (h2) - sc-401254-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB CRISPR Activation Plasmid (h) - sc-401254-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB CRISPR Activation Plasmid (h2) - sc-401254-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB Lentiviral Activation Particles (h) - sc-401254-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB Lentiviral Activation Particles (h2) - sc-401254-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PCB siRNA (h) - sc-45531 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PCB shRNA Plasmid (h) - sc-45531-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PCB shRNA (h) Lentiviral Particles - sc-45531-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pyruvate Carboxylase RNAi - H00005091-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Pyruvate Carboxylase RNAi - H00005091-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU134851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16388 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16388 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03805 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03805

PC siRNA (Human) - CRH3385 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human PC siRNA - orb263887 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PC shRNA Plasmid (Human) - CHH3385 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PC miRNA 3'UTR clone - MiUTR1H-07551 from Creative biogene

Species Reactivities Human

PC miRNA 3'UTR clone - MiUTR3H-10228 from Creative biogene

Species Reactivities Human

PC miRNA 3'UTR clone - MiUTR3H-10229 from Creative biogene

Species Reactivities Human
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