PC

Gene Symbol	PC
Entrez Gene	5091
Alt Symbol	PCB
Species	Human
Gene Type	protein-coding
Description	pyruvate carboxylase
Other Description	pyruvate carboxylase, mitochondrial|pyruvic carboxylase
Swissprots	P11498 B4DN00 Q16705
Accessions	CBF60260 CBF61085 CBF62141 CBF64322 CBF68536 CBF95786 CBU85504 CBU86113 CBU87017 CBU89198 CBU93410 CBV09306 EAW74568 EAW74569 EAW74570 EAW74571 EAW74572 P11498 AK297705 BAG60062 BC011617 AAH11617 CN267865 DA542083 K02282 AAA60033 M26122 AAA36423 S72370 AAB31500 U04641 AAA99537 U30889 U30890 U30891 AAA82937 XM_005274031 XP_005274088 XM_005274032 XP_005274089 XM_006718577 XP_006718640 XM_006718578 XP_006718641 XM_006718579 XP_006718642 XM_011545085 XP_011543387 XM_011545086 XP_011543388 XM_011545087 XP_011543389 XM_011545088 XP_011543390 NM_000920 NP_000911 NM_001040716 NP_001035806 NM_022172 NP_071504
Function	Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
Subcellular Location	Mitochondrion matrix.
Top Pathways	Citrate cycle (TCA cycle), Pyruvate metabolism, Biosynthesis of amino acids, Carbon metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PCB protein fragment - ab127137 from Abcam Category Protein Source E. coli Species Human

PC / Pyruvate Carboxylase Antibody Blocking Peptide - LS-E1717 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PC / Pyruvate Carboxylase Antibody Blocking Peptide - LS-E21809 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PC / Pyruvate Carboxylase Antibody Blocking Peptide - LS-E26601 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Pyruvate Carboxylase Protein - H00005091-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PC-Antibody-N-term-Blocking-peptide - BP12494a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Pyruvate Carboxylase blocking peptide - GTX88823-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

PC Immunizing peptide - orb50392 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PC Blocking Peptide - 33R-8614 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Pyruvate Carboxylase Blocking Peptide - abx063051 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Monkey, Pig, Sheep, Zebrafish

PCB Peptide - AC21-1437-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Pyruvic carboxylase (PC) - H00005091-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Pyruvic carboxylase (PC) - H00005091-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Pyruvate carboxylase Peptide - 46-255P from ProSci Category Peptide Species Mouse

PC fusion protein - Ag8857 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PC fusion protein - Ag8846 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human PC, GST-tagged - PC-1545H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PC - PC-908H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Pyruvate Carboxylase (PC) - RPH430Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Pyruvate Carboxylase (PC) - RPH430Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Pyruvate Carboxylase (PC) - RPH430Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Pyruvate Carboxylase Blocking Peptide - CBP1857 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Monkey, Pig, Sheep, Zebrafish

PCB Peptide - BS5841P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Pyruvate Carboxylase (PC) - RPH430Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Protein C (PROC) - RPA734Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Search more