| Gene Symbol |
HSD17B2
|
| Entrez Gene |
3294
|
| Alt Symbol |
EDH17B2, HSD17, SDR9C2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hydroxysteroid (17-beta) dehydrogenase 2
|
| Other Description |
17-beta-HSD 2|17-beta-hydroxysteroid dehydrogenase type 2|20 alpha-hydroxysteroid dehydrogenase|20-alpha-HSD|E2DH|estradiol 17-beta-dehydrogenase 2|microsomal 17-beta-hydroxysteroid dehydrogenase|short chain dehydrogenase/reductase family 9C member 2|short chain dehydrogenase/reductase family 9C, member 2|testosterone 17-beta-dehydrogenase
|
| Swissprots |
B2R7T4 P37059
|
| Accessions |
AAC41917 AAP78485 EAW95519 P37059 AK223001 BAD96721 AK313109 BAG35931 AU139034 BC009581 AAH09581 BC059170 AAH59170 BM670647 BP270993 DQ893100 ABM84026 DQ896372 ABM87371 L11708 AAA03562 XR_243405 NM_002153 NP_002144
|
| Function |
Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Top Pathways |
Steroid hormone biosynthesis, Ovarian steroidogenesis
|
