Gene Symbol | HSD17B2 |
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Entrez Gene | 3294 |
Alt Symbol | EDH17B2, HSD17, SDR9C2 |
Species | Human |
Gene Type | protein-coding |
Description | hydroxysteroid (17-beta) dehydrogenase 2 |
Other Description | 17-beta-HSD 2|17-beta-hydroxysteroid dehydrogenase type 2|20 alpha-hydroxysteroid dehydrogenase|20-alpha-HSD|E2DH|estradiol 17-beta-dehydrogenase 2|microsomal 17-beta-hydroxysteroid dehydrogenase|short chain dehydrogenase/reductase family 9C member 2|short chain dehydrogenase/reductase family 9C, member 2|testosterone 17-beta-dehydrogenase |
Swissprots | B2R7T4 P37059 |
Accessions | AAC41917 AAP78485 EAW95519 P37059 AK223001 BAD96721 AK313109 BAG35931 AU139034 BC009581 AAH09581 BC059170 AAH59170 BM670647 BP270993 DQ893100 ABM84026 DQ896372 ABM87371 L11708 AAA03562 XR_243405 NM_002153 NP_002144 |
Function | Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | Steroid hormone biosynthesis, Ovarian steroidogenesis |
17β-HSD2 (G-15) - sc-66408 from Santa Cruz Biotechnology
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Anti-HSD17B2 antibody - ab196784 from Abcam
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Anti-HSD17B2 antibody - ab187183 from Abcam
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Anti-HSD17B2 antibody - ab103161 from Abcam
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Anti-HSD17B2 antibody - ab103665 from Abcam
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Anti-HSD17B2 antibody - ab67179 from Abcam
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Anti-HSD17B2 antibody - ab131092 from Abcam
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Anti-HSD17B2 antibody - ab200441 from Abcam
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Anti-HSD17B2 antibody [3E9] - ab127992 from Abcam
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Anti-HSD17B2 Antibody (aa265-294, AP) - LS-C215173 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294, APC) - LS-C215174 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294, FITC) - LS-C215177 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294, Biotin) - LS-C215176 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294, Azide-free, HRP) - LS-C215178 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody - LS-C308321 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa373-387) - LS-C312759 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294, PE) - LS-C215179 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody - LS-C310667 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody - LS-C311231 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa270-300) - LS-C322102 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody - LS-C341395 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (aa265-294) - LS-C165034 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (clone 4F10) - LS-C173853 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody - LS-C331804 from LifeSpan Bioscience
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Anti-HSD17B2 Antibody (clone 3E9) - LS-C173886 from LifeSpan Bioscience
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