Gene Symbol |
ANKRD1
|
Entrez Gene |
27063
|
Alt Symbol |
ALRP, C-193, CARP, CVARP, MCARP, bA320F15.2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ankyrin repeat domain 1 (cardiac muscle)
|
Other Description |
ankyrin repeat domain-containing protein 1|cardiac ankyrin repeat protein|cytokine-inducible gene C-193 protein|cytokine-inducible nuclear protein|liver ankyrin repeat domain 1
|
Swissprots |
Q96LE7 Q15327
|
Accessions |
EAW50116 Q15327 AK290960 BAF83649 AU139209 AY903446 AAX23581 BC005191 AAH05191 BC018667 AAH18667 DQ892852 ABM83778 DQ896099 ABM87098 X83703 CAA58676 NM_014391 NP_055206
|
Function |
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}.
|
Tissue Specificity |
Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}.
|