Gene Symbol | ANKRD1 |
---|---|
Entrez Gene | 27063 |
Alt Symbol | ALRP, C-193, CARP, CVARP, MCARP, bA320F15.2 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 1 (cardiac muscle) |
Other Description | ankyrin repeat domain-containing protein 1|cardiac ankyrin repeat protein|cytokine-inducible gene C-193 protein|cytokine-inducible nuclear protein|liver ankyrin repeat domain 1 |
Swissprots | Q96LE7 Q15327 |
Accessions | EAW50116 Q15327 AK290960 BAF83649 AU139209 AY903446 AAX23581 BC005191 AAH05191 BC018667 AAH18667 DQ892852 ABM83778 DQ896099 ABM87098 X83703 CAA58676 NM_014391 NP_055206 |
Function | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |
Tissue Specificity | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |