Gene Symbol | ANKRD1 |
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Entrez Gene | 27063 |
Alt Symbol | ALRP, C-193, CARP, CVARP, MCARP, bA320F15.2 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 1 (cardiac muscle) |
Other Description | ankyrin repeat domain-containing protein 1|cardiac ankyrin repeat protein|cytokine-inducible gene C-193 protein|cytokine-inducible nuclear protein|liver ankyrin repeat domain 1 |
Swissprots | Q96LE7 Q15327 |
Accessions | EAW50116 Q15327 AK290960 BAF83649 AU139209 AY903446 AAX23581 BC005191 AAH05191 BC018667 AAH18667 DQ892852 ABM83778 DQ896099 ABM87098 X83703 CAA58676 NM_014391 NP_055206 |
Function | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |
Tissue Specificity | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. {ECO:0000269|PubMed:15805281, ECO:0000269|PubMed:7730328}. |
CARP CRISPR/Cas9 KO Plasmid (h) - sc-401842 from Santa Cruz Biotechnology
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CARP HDR Plasmid (h) - sc-401842-HDR from Santa Cruz Biotechnology
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CARP Double Nickase Plasmid (h) - sc-401842-NIC from Santa Cruz Biotechnology
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CARP Double Nickase Plasmid (h2) - sc-401842-NIC-2 from Santa Cruz Biotechnology
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CARP CRISPR Activation Plasmid (h) - sc-401842-ACT from Santa Cruz Biotechnology
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CARP CRISPR Activation Plasmid (h2) - sc-401842-ACT-2 from Santa Cruz Biotechnology
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CARP Lentiviral Activation Particles (h) - sc-401842-LAC from Santa Cruz Biotechnology
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CARP Lentiviral Activation Particles (h2) - sc-401842-LAC-2 from Santa Cruz Biotechnology
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CARP siRNA (h) - sc-37731 from Santa Cruz Biotechnology
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CARP shRNA Plasmid (h) - sc-37731-SH from Santa Cruz Biotechnology
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CARP shRNA (h) Lentiviral Particles - sc-37731-V from Santa Cruz Biotechnology
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ANKRD1 RNAi - H00027063-R01 from Novus Biologicals
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MISSION® esiRNA - EHU014641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3171 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06674 from Sigma-Aldrich
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ANKRD1 siRNA (Human) - CRH8941 from Cohesion Biosciences
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ANKRD1 - MBS8201744 from MyBioSource
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shRNA set against Human ANKRD1 (NM_014391.2) - SHH236526 from Creative biogene
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shRNA set against Human ANKRD1(NM_014391.2) - SHG059239 from Creative biogene
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ANKRD1 shRNA Plasmid (Human) - CHH8941 from Cohesion Biosciences
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ANKRD1 miRNA 3'UTR clone - MiUTR1H-00378 from Creative biogene
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