AGAP3

Gene Symbol AGAP3
Entrez Gene 116988
Alt Symbol AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3
Species Human
Gene Type protein-coding
Description ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Other Description CRAM-associated GTPase|CRMP (collapsin response mediator protein) associated|MR1-interacting protein|arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3|centaurin, gamma 3|centaurin-gamma-3
Swissprots E9PAL8 Q96P47 Q96RK3 Q59EN0 B3KNZ8
Accessions CCQ43753 EAL24502 EAW54024 EAW54025 EAW54026 EAW54027 EAW54028 EAW54029 Q96P47 AB209781 BAD93018 AF359283 AAK48932 AF413079 AAL04173 AK027415 BAB55097 AK055393 BAG51510 AK091771 AK096352 BAC04766 AL442089 CAC09448 BC020426 BC037543 BC044644 AAH44644 BC048300 AAH48300 BC069236 BU615528 DA771207 EU831441 ACE87128 EU831533 ACE86452 XM_005249942 XP_005249999 XM_005249943 XP_005250000 XM_011515780 XP_011514082 NM_001042535 NP_001036000 NM_001281300 NP_001268229 NM_001308304 NP_001295233 NM_001308305 NP_001295234 NM_031946 NP_114152
Function GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway. {ECO:0000269|PubMed:16461359, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16461359}. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:15381706, ECO:0000269|PubMed:16461359}.
Top Pathways Endocytosis

Centaurin γ3 (A-10) - sc-393553 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Centaurin γ3 (A-10): sc-393553. Western blot analysis of Centaurin γ3 expression in HeLa (A) and T98G (B) whole cell lysates and human heart (C) and mouse brain (D) tissue extracts.

Centaurin γ3 (E-8) - sc-271793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Centaurin γ3 (E-8): sc-271793. Western blot analysis of Centaurin γ3 expression in non-transfected 293T: sc-117752 (A) and mouse Centaurin γ3 transfected 293T: sc-119171 (B) whole cell lysates.

Centaurin γ3 (C-17) - sc-47830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Centaurin γ3 (C-17): sc-47830. Western blot analysis of Centaurin γ3 expression in non-transfected: sc-117752 (A) and mouse Centaurin γ3 transfected: sc-119171 (B) 293T whole cell lysates.

Centaurin γ3 (H-50) - sc-135212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CENTG3 antibody - ab108523 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CENTG3 antibody (ab108523) at 1/500 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal lung lysateLane 3 : Human fetal kidney lysate

Anti-CENTG3 antibody - ab115459 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab115459 at 5 &microg/ml staining CENTG3 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CENTG3 antibody - ab15969 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab15969 at 5ug/ml staining CENTG3 in human kidney tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). A AP-staining procedure was used for detection.

Anti-CENTG3 antibody - N-terminal - ab173083 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CENTG3 antibody - N-terminal (ab173083) at 1/100 dilution + U937 cell line lysate at 35 µg

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, Azide-free, HRP) - LS-C251011 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody - LS-C178418 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, PE) - LS-C251013 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa190-217) - LS-C161017 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
AGAP3 Antibody western blot of U937 cell line lysates (35 ug/lane). The AGAP3 antibody detected the AGAP3 protein (arrow).

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, AP) - LS-C252833 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, FITC) - LS-C252835 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, APC) - LS-C252834 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217, Biotin) - LS-C252836 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa1-50) - LS-C288926 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (C-Terminus) - LS-C186914 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human 293T. AGAP3 antibody dilution 1.0 ug/ml.

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa825-875) - LS-C288927 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa189-217) - LS-C319367 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGAP3 / CENTG3 / MRIP-1 Antibody (aa899-911) IHC-plus™ - LS-B2283 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-AGAP3 / CENTG3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2283 concentration 5 ug/ml.

AGAP3 Antibody - NB100-1323 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: AGAP3 Antibody [NB100-1323] - (5ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

AGAP3 Antibody - NBP1-40081 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: AGAP3 Antibody [NBP1-40081] - Analysis of anti-AGAP3 / CENTG3 antibody with human kidney at concentration 5 ug/ml.

AGAP3 Antibody - NBP1-22968 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: AGAP3 Antibody [NBP1-22968] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CENTG3 antibody used for IP at 10 mcg/mg lysate. CENTG3 was also immunoprecipitated by rabbit anti-CENTG3 antibody NBP1-22969, which recognizes a downstream epitope.

AGAP3 Antibody - NBP1-85685 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: AGAP3 Antibody [NBP1-85685] - Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.
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