Gene Symbol | AGAP3 |
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Entrez Gene | 116988 |
Alt Symbol | AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3 |
Species | Human |
Gene Type | protein-coding |
Description | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 |
Other Description | CRAM-associated GTPase|CRMP (collapsin response mediator protein) associated|MR1-interacting protein|arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3|centaurin, gamma 3|centaurin-gamma-3 |
Swissprots | E9PAL8 Q96P47 Q96RK3 Q59EN0 B3KNZ8 |
Accessions | CCQ43753 EAL24502 EAW54024 EAW54025 EAW54026 EAW54027 EAW54028 EAW54029 Q96P47 AB209781 BAD93018 AF359283 AAK48932 AF413079 AAL04173 AK027415 BAB55097 AK055393 BAG51510 AK091771 AK096352 BAC04766 AL442089 CAC09448 BC020426 BC037543 BC044644 AAH44644 BC048300 AAH48300 BC069236 BU615528 DA771207 EU831441 ACE87128 EU831533 ACE86452 XM_005249942 XP_005249999 XM_005249943 XP_005250000 XM_011515780 XP_011514082 NM_001042535 NP_001036000 NM_001281300 NP_001268229 NM_001308304 NP_001295233 NM_001308305 NP_001295234 NM_031946 NP_114152 |
Function | GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway. {ECO:0000269|PubMed:16461359, ECO:0000305}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16461359}. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15381706, ECO:0000269|PubMed:16461359}. |
Top Pathways | Endocytosis |
Human CENTG3 peptide - ab23291 from Abcam
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Human CENTG3 protein fragment - ab165118 from Abcam
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AGAP3 / CENTG3 / MRIP-1 Antibody Blocking Peptide - LS-E4963 from LifeSpan Bioscience
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AGAP3 / CENTG3 / MRIP-1 Antibody Blocking Peptide - LS-E25615 from LifeSpan Bioscience
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AGAP3 / CENTG3 / MRIP-1 Antibody Blocking Peptide - LS-E24809 from LifeSpan Bioscience
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AGAP3 Partial Recombinant Protein - H00116988-Q01 from Novus Biologicals
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AGAP3-Antibody-N-term-Blocking-Peptide - BP17355a from Abgent, a WuXi AppTec company
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CENTG3 blocking peptide - GTX15969-PEP from GeneTex
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CENTG3 Peptide - AC21-0446-P from Abcore
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AGAP3 / CENTG3 - H00116988-Q01-10 from Acris Antibodies
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AGAP3 / CENTG3 - H00116988-Q01-25 from Acris Antibodies
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MRIP1 Peptide - 45-902P from ProSci
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Recombinant Human Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3(AGAP3) ,partial - CSB-YP846681HU CSB-EP846681HU CSB-BP846681HU CSB-MP846681HU from Cusabio
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AGAP3 / CENTG3 (transcript variant 1) - TP312440 from Acris Antibodies
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Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3(AGAP3) ,partial, Recombinant Protein - MBS1361337 from MyBioSource
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CENTG3/MRIP1, Peptide - MBS426453 from MyBioSource
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AGAP3 Recombinant Protein Antigen - NBP1-85685PEP from Novus Biologicals
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AGAP3 Peptide, Human - M34GP00361H from Creative Peptides
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AGAP3 fusion protein - Ag26662 from Proteintech Group
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AGAP3 Immunizing peptide - orb17822 from Biorbyt
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AGAP3 fusion protein - Ag26671 from Proteintech Group
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