RAP2A

Gene Symbol RAP2A
Entrez Gene 5911
Alt Symbol K-REV, KREV, RAP2, RbBP-30
Species Human
Gene Type protein-coding
Description RAP2A, member of RAS oncogene family
Other Description RAP2, member of RAS oncogene family (K-rev)|ras-related protein Rap-2a
Swissprots P10114 Q5JSC1 Q5JSC2 B2RCJ1
Accessions CAA00806 EAX08974 P10114 AF205602 AAN71845 AF493914 AAM12628 AK090533 AK094586 AK311202 AK315139 BAG37588 BC022356 BC041333 AAH41333 BC047495 BC070031 AAH70031 CB215818 DA493957 DB480985 EU832309 ACE87566 EU832393 ACE86878 X12534 CAA31052 NM_021033 NP_066361
Function Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. {ECO:0000269|PubMed:14966141, ECO:0000269|PubMed:15342639, ECO:0000269|PubMed:16246175, ECO:0000269|PubMed:16540189, ECO:0000269|PubMed:18930710, ECO:0000269|PubMed:20159449}.
Subcellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. Note=May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995). Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443). {ECO:0000269|PubMed:23894443, ECO:0000269|PubMed:7962206, ECO:0000269|PubMed:8391995}.

Rap 2A CRISPR/Cas9 KO Plasmid (h) - sc-403109 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A HDR Plasmid (h) - sc-403109-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A Double Nickase Plasmid (h) - sc-403109-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A Double Nickase Plasmid (h2) - sc-403109-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A CRISPR Activation Plasmid (h) - sc-403109-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A CRISPR Activation Plasmid (h2) - sc-403109-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A Lentiviral Activation Particles (h) - sc-403109-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A Lentiviral Activation Particles (h2) - sc-403109-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A siRNA (h) - sc-36386 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rap 2A shRNA Plasmid (h) - sc-36386-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rap 2A shRNA (h) Lentiviral Particles - sc-36386-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rap2A RNAi - H00005911-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU034761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17950 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17950 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR14103 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr14103

RAP2A siRNA (Human) - CRH3997 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RAP2A - MBS8233338 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Rap 2A CRISPR/Cas9 KO Plasmid (h2) - sc-403109-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rap 2A HDR Plasmid (h2) - sc-403109-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human RAP2A siRNA - orb264499 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RAP2A shRNA Plasmid (Human) - CHH3997 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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