FCGR2B

Gene Symbol	FCGR2B
Entrez Gene	2213
Alt Symbol	CD32, CD32B, FCG2, FCGR2, IGFR2
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgG, low affinity IIb, receptor (CD32)
Other Description	CDw32|Fc fragment of IgG, low affinity II, receptor for (CD32)|Fc fragment of IgG, low affinity IIb, receptor for (CD32)|Fc gamma RIIb|fc-gamma RII-b|fc-gamma-RIIb|fcRII-b|igG Fc receptor II-b|low affinity immunoglobulin gamma Fc region receptor II-b
Swissprots	Q5VXA9 O95649 P31994 Q53X85 A6H8N3 Q8NIA1
Accessions	ABK41919 BAC54013 BAC54014 BAC54015 BAC54016 BAC54017 BAC54018 BAC54019 BAC54020 EAW90679 EAW90680 EAW90681 EAW90682 P31994 AB050934 BAB92093 AB051387 BAB92094 AB209585 BAD92822 AF543826 AAQ11739 AI692546 AK308150 AW452813 BC031992 AAH31992 BC141826 AAI41827 BC146678 AAI46679 BC148273 AAI48274 CB988406 CR407635 CAG28563 DC381078 DQ894525 ABM85451 H04104 M28696 AAA36051 M31933 AAA35841 M31934 AAA35842 M31935 AAA35843 U87560 AAD00627 U87561 AAD00628 U87562 AAD00629 U87563 AAD00630 U87564 AAD00631 U87565 AAD00632 U87566 AAD00633 U87567 AAD00634 U87568 AAD00635 U87569 AAD00636 U87570 AAD00637 U87571 AAD00638 U87572 AAD00639 U87573 AAD00640 U87574 AAD00641 U87575 AAD00642 U87576 AAD00643 U87577 AAD00644 X17653 CAA35644 X52473 CAA36713 X62573 XM_011509292 XP_011507594 NM_001002273 NP_001002273 NM_001002274 NP_001002274 NM_001002275 NP_001002275 NM_001190828 NP_001177757 NM_004001 NP_003992
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Top Pathways	B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Phagosome, Staphylococcus aureus infection, Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Fc-gamma RIIB/C Human ELISA Kit - ab113333 from Abcam Category ELISA Kit Prices $749.00 Sizes 1 x 96 tests Sensitivity < 85 pg/ml Range 78.13 pg/ml - 5000 pg/ml

Human CD32B ELISA Kit - LS-F2970 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 1 pg/ml Range 46.9 - 3000 pg/ml

Mouse/Human/Rat Phospho-CD32B (Tyr292) Cell-Based ELISA Kit - LS-F1246 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat FCGR2 / CD32 ELISA Kit (Cell-Based ELISA) - LS-F1868 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.096-23.33 ng/ml

Mouse FCGR2 / CD32 ELISA Kit (Sandwich ELISA) - LS-F491 from LifeSpan Bioscience Category ELISA Kit Prices $620.00, $1,090.00, $2,380.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.096 ng/ml Range 0.096-23.33 ng/ml

Mouse FCGR2 / CD32 ELISA Kit (Sandwich ELISA) - LS-F10496 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.096-23.33 ng/ml

Human FcgRIIBC ELISA Kit - RAB0181 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human Fc gamma RIIB/C (CD32b/c) DuoSet ELISA - DY1875 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 93.80 - 3,000 pg/mL

Mouse Fc gamma RIIB/CD32b DuoSet ELISA - DY1460 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Human, ELISA Kit - E-EL-H1743 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 28.125 Range 46.875-3000pg/mL

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), Human, ELISA Kit - CSB-EL008541HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), Human, ELISA Kit - E01L0110 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 10-250ng/ml

Low affinity immunoglobulin gamma Fc region receptor II-c (FCGR2C), Human, ELISA Kit - CSB-EL008542HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Rabbit, ELISA Kit - E-EL-RB1522 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Chicken, ELISA Kit - E-EL-Ch0899 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Porcine, ELISA Kit - E-EL-P0182 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Sheep, ELISA Kit - E-EL-S0619 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Guinea Pig, ELISA Kit - E-EL-GP1110 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Receptor II for the Fc Fragment of IgG, FcyR II/CD32, Monkey, ELISA Kit - E-EL-MK0690 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

FCGR2B (Human) IP-WB Antibody Pair - H00002213-PW3 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FCGR2B (Human) ELISA Kit - KA2177 from Acris Antibodies Category ELISA Kit Prices $650.00 Sizes 1 kit

Human FcgRIIBC ELISA - ELH-FcgRIIBC from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 85 pg/ml Range 85 pg/ml - 5000 pg/ml

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), ELISA Kit - MBS7228969 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), ELISA Kit - MBS7252822 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), ELISA Kit - MBS7203928 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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