FCGR2B

Gene Symbol FCGR2B
Entrez Gene 2213
Alt Symbol CD32, CD32B, FCG2, FCGR2, IGFR2
Species Human
Gene Type protein-coding
Description Fc fragment of IgG, low affinity IIb, receptor (CD32)
Other Description CDw32|Fc fragment of IgG, low affinity II, receptor for (CD32)|Fc fragment of IgG, low affinity IIb, receptor for (CD32)|Fc gamma RIIb|fc-gamma RII-b|fc-gamma-RIIb|fcRII-b|igG Fc receptor II-b|low affinity immunoglobulin gamma Fc region receptor II-b
Swissprots Q5VXA9 O95649 P31994 Q53X85 A6H8N3 Q8NIA1
Accessions ABK41919 BAC54013 BAC54014 BAC54015 BAC54016 BAC54017 BAC54018 BAC54019 BAC54020 EAW90679 EAW90680 EAW90681 EAW90682 P31994 AB050934 BAB92093 AB051387 BAB92094 AB209585 BAD92822 AF543826 AAQ11739 AI692546 AK308150 AW452813 BC031992 AAH31992 BC141826 AAI41827 BC146678 AAI46679 BC148273 AAI48274 CB988406 CR407635 CAG28563 DC381078 DQ894525 ABM85451 H04104 M28696 AAA36051 M31933 AAA35841 M31934 AAA35842 M31935 AAA35843 U87560 AAD00627 U87561 AAD00628 U87562 AAD00629 U87563 AAD00630 U87564 AAD00631 U87565 AAD00632 U87566 AAD00633 U87567 AAD00634 U87568 AAD00635 U87569 AAD00636 U87570 AAD00637 U87571 AAD00638 U87572 AAD00639 U87573 AAD00640 U87574 AAD00641 U87575 AAD00642 U87576 AAD00643 U87577 AAD00644 X17653 CAA35644 X52473 CAA36713 X62573 XM_011509292 XP_011507594 NM_001002273 NP_001002273 NM_001002274 NP_001002274 NM_001002275 NP_001002275 NM_001190828 NP_001177757 NM_004001 NP_003992
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Top Pathways B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Phagosome, Staphylococcus aureus infection, Osteoclast differentiation

CD32 CRISPR/Cas9 KO Plasmid (h) - sc-416631 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 HDR Plasmid (h) - sc-416631-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 Double Nickase Plasmid (h) - sc-416631-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 Double Nickase Plasmid (h2) - sc-416631-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 CRISPR Activation Plasmid (h) - sc-416631-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 CRISPR Activation Plasmid (h2) - sc-416631-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 Lentiviral Activation Particles (h) - sc-416631-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32 Lentiviral Activation Particles (h2) - sc-416631-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD32-B siRNA (h) - sc-42774 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD32-B shRNA Plasmid (h) - sc-42774-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD32-B shRNA (h) Lentiviral Particles - sc-42774-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fc gamma RIIB/CD32b RNAi - H00002213-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Fc gamma RIIB/CD32b RNAi - H00002213-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Fc gamma RIIB/CD32b RNAi - H00002213-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU117131 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN8590 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8590 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FCGR2B siRNA (Human) - CRH1547 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Fc gamma RIIB/CD32b RNAi - H00002213-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FCGR2B - MBS8200919 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FCGR2B (NM_004001.4) - SHH293717 from Creative biogene

Category siRNA
Species Reactivities Human

Human FCGR2B siRNA - orb262049 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FCGR2B shRNA Plasmid (Human) - CHH1547 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FCGR2B miRNA 3'UTR clone - MiUTR3H-06935 from Creative biogene

Species Reactivities Human

FCGR2B miRNA 3'UTR clone - MiUTR3H-06936 from Creative biogene

Species Reactivities Human
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