AKR1D1

Gene Symbol	AKR1D1
Entrez Gene	6718
Alt Symbol	3o5bred, CBAS2, SRD5B1
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member D1
Other Description	3-oxo-5-beta-steroid 4-dehydrogenase|delta 4-3-ketosteroid-5-beta-reductase|delta(4)-3-ketosteroid 5-beta-reductase|delta(4)-3-oxosteroid 5-beta-reductase|steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
Swissprots	P51857 A1L4P6 B4DPN8 B4DPN3 A8K060
Accessions	AAG39381 EAL24049 EAW83881 EAW83882 P51857 AK058142 BAB71682 AK289425 BAF82114 AK298421 BAG60645 AK298428 BAG60650 BC130625 AAI30626 BC130627 AAI30628 BG210362 CB111926 FM160741 CAQ55951 FM160742 CAQ55952 FM160743 CAQ55953 HQ258384 ADR83138 Z28339 CAA82193 NM_001190906 NP_001177835 NM_001190907 NP_001177836 NM_005989 NP_005980
Function	Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7- alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4- cholesten-3-one can also act as substrates. {ECO:0000269|PubMed:11342103}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in liver. Expressed in testis and weakly in colon. {ECO:0000269|PubMed:11342103}.
Top Pathways	Primary bile acid biosynthesis, Steroid hormone biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-AKR1D1-cDNA-Clone - DC14720 from Abgent, a WuXi AppTec company Prices $440.10 Sizes 10 µg Species Human Accession BC130625

AKR1D1 - MBS1267195 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC130625

Human AKR1D1 ORF Clone(NM_005989.3) - CDCL153527 from Creative Biomart Species Human Accession NM_005989.3

Human AKR1D1 ORF Clone(NM_001190906.1) - CDCR358093 from Creative Biomart Species Human Accession NM_001190906.1

Human AKR1D1 ORF Clone(NM_001190906.1) - CDCR358094 from Creative Biomart Species Human Accession NM_001190906.1

Human AKR1D1 ORF Clone(NM_001190907.1) - CDCR358096 from Creative Biomart Species Human Accession NM_001190907.1

Human AKR1D1 ORF Clone(NM_001190907.1) - CDCR358101 from Creative Biomart Species Human Accession NM_001190907.1

Human AKR1D1 Gene ORF cDNA clone in cloning vector - HG15643-G from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15643-ANG from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15643-ACG from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15643-NF from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid - HG15643-UT from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15643-NY from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15643-ACR from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15643-ANR from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15643-CF from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15643-NM from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15643-CM from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-His tag - HG15643-CH from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, N-His tag - HG15643-NH from Sino Biological Species Human

Human AKR1D1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15643-CY from Sino Biological Species Human

Human AKR1D1 ORF clone (NM_001190907.1) - CDCR026424 from Creative biogene Species Human

Human AKR1D1 ORF clone (NM_001190906.1) - CDCR026426 from Creative biogene Species Human

Human AKR1D1 ORF Clone (BC130625) - CDCS409222 from Creative biogene Species Human Accession P51857

Human AKR1D1 ORF clone (BC130625) - CDCB157973 from Creative biogene Species Human

Search more