AKR1D1

Gene Symbol	AKR1D1
Entrez Gene	6718
Alt Symbol	3o5bred, CBAS2, SRD5B1
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member D1
Other Description	3-oxo-5-beta-steroid 4-dehydrogenase|delta 4-3-ketosteroid-5-beta-reductase|delta(4)-3-ketosteroid 5-beta-reductase|delta(4)-3-oxosteroid 5-beta-reductase|steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
Swissprots	P51857 A1L4P6 B4DPN8 B4DPN3 A8K060
Accessions	AAG39381 EAL24049 EAW83881 EAW83882 P51857 AK058142 BAB71682 AK289425 BAF82114 AK298421 BAG60645 AK298428 BAG60650 BC130625 AAI30626 BC130627 AAI30628 BG210362 CB111926 FM160741 CAQ55951 FM160742 CAQ55952 FM160743 CAQ55953 HQ258384 ADR83138 Z28339 CAA82193 NM_001190906 NP_001177835 NM_001190907 NP_001177836 NM_005989 NP_005980
Function	Efficiently catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone and testosterone to 5-beta-reduced metabolites. The bile acid intermediates 7- alpha,12-alpha-dihydroxy-4-cholesten-3-one and 7-alpha-hydroxy-4- cholesten-3-one can also act as substrates. {ECO:0000269|PubMed:11342103}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in liver. Expressed in testis and weakly in colon. {ECO:0000269|PubMed:11342103}.
Top Pathways	Primary bile acid biosynthesis, Steroid hormone biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AKR1D1 full length protein - ab104758 from Abcam Category Protein Prices $235.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human AKR1D1 full length protein - ab125483 from Abcam Category Protein Prices $188.00 Sizes 20 µg Source E. coli Species Human

AKR1D1 Antibody Blocking Peptide - LS-E4367 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1D1 Antibody Blocking Peptide - LS-E22252 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AKR1D1 Partial Recombinant Protein - H00006718-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

AKR1D1 Recombinant Protein - H00006718-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AKR1D1 Protein - NBP1-51026 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

AKR1D1-Antibody-Center-Blocking-Peptide - BP16670c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human AKR1D1 protein - orb167876 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

AKR1D1 Blocking Peptide - 33R-10271 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

AKR1D1 protein (His tag) - 80R-1711 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

AKR1D1 / SRD5B1 (1-326, His-tag) - AR09893PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

AKR1D1 / SRD5B1 (1-326, His-tag) - AR09893PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

AKR1D1 / SRD5B1 - H00006718-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

AKR1D1 / SRD5B1 - H00006718-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

AKR1D1 / SRD5B1 - H00006718-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AKR1D1 / SRD5B1 - H00006718-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Aldo-Keto Reductase Family 1 Member D1, Human Recombinant, His Tag - 228-12250-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

AKR1D1, 1-326aa, Human, His tag, E.coli - 01-P0953 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

AKR1D1 fusion protein - Ag21009 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

AKR1D1 Human - ENPS-105 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human AKR1D1 - BP000862-ENZ-098 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

AKR1D1, 1-326aa, Recombinant Protein - GWB-P1085F from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

AKR1D1 Human Protein - GWB-BSP124 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human AKR1D1, His-tagged - AKR1D1-26148TH from Creative Biomart Category Protein Source E. coli

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