TNXB

Gene Symbol TNXB
Entrez Gene 7148
Alt Symbol EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS
Species Human
Gene Type protein-coding
Description tenascin XB
Other Description growth-inhibiting protein 45|hexabrachion-like protein|tenascin XB1|tenascin XB2|tenascin-X
Swissprots Q5ST74 Q9UC11 Q5SQD3 Q9UC12 Q59GU7 Q08AM0 Q9UC13 P78530 Q9UC10 Q9UMG7 Q8N4R1 P22105 Q7L8Q4 Q9NPK9 Q08424 Q08AM1 P78531
Accessions AAB47488 AAB67981 CAA50740 CAA74110 CAB89296 CAB89297 CAB89298 CAB89299 CAB89300 EAX03572 EAX03573 EAX03574 EAX03575 EAX03576 EAX03577 EAX03578 EAX03579 P22105 AB209012 BAD92249 AK310080 AL044866 BC033740 AAH33740 BC071883 AAH71883 BC125114 AAI25115 BC125115 AAI25116 BC130037 AAI30038 BI010479 BP233293 BP420628 BQ446909 EU219621 ACA14133 JF432266 ADZ15483 M25813 AAA35884 U24488 AAB41287 U52699 AAC50880 U52700 AAC50882 X71923 CAA50739 X71927 Y13782 CAA74109 Y17865 CAA76899 Y17866 CAA76900 Y17867 CAA76901 Y17868 CAA76902 NM_019105 NP_061978 NM_032470 NP_115859
Function Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. {ECO:0000269|PubMed:17033827}.
Subcellular Location Secreted, extracellular space, extracellular matrix.
Tissue Specificity Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB- short is only expressed in the adrenal gland.
Top Pathways Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

Tenascin-X (F-11) - sc-271594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tenascin-X (F-11): sc-271594. Western blot analysis of Tenascin-X expression in non-transfected: sc-117752 (A) and human Tenascin-X transfected: sc-115036 (B) 293T whole cell lysates.

Tenascin-X (C-13) - sc-5498 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Tenascin-X (C-13): sc-5498. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing extracellular localization.

Tenascin-X (H-10) - sc-166456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tenascin-X (H-10): sc-166456. Western blot analysis of Tenascin-X expression in non-transfected: sc-117752 (A) and human Tenascin-X transfected: sc-115036 (B) 293T whole cell lysates.

Tenascin-X (N-17) - sc-5495 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Tenascin-X (H-90) - sc-25717 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tenascin-X (H-90): sc-25717. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of epidermal and adnexal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-TNXB antibody - ab198871 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling TNXB with ab198871 at 1/40 dilution.

Anti-TNXB antibody - ab111270 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using 1/50 ab111270. The picture on the right is treated with the synthesized peptide

Anti-TNXB antibody - ab67586 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-TNXB antibody (ab67586) at 1/500 dilutionLane 1 : TNXB transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-TNXB antibody - ab172253 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TNXB antibody (ab172253) at 1 µg/mlLane 1 : TNXB transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateSecondaryLane 1 : Goat Anti-Rabbit IgG at 1/7500 dilutionLane 2 : Goat Anti-Rabbit IgGd at 1/7500 dilution

Anti-TNXB antibody [SP230] - ab183346 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP230
Immunohistochemical analysis of paraffin embedded Human mesothelioma tissue labeling TNXB with ab183346 at 1/100 dilution.

Anti-TNXB / Tenascin XB Antibody - LS-C342248 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNXB / Tenascin XB Antibody (aa1761-1810) - LS-C199671 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using TNXB Antibody. The sample on the right was incubated with synthetic peptide.

Anti-TNXB / Tenascin XB Antibody (clone SP230) - LS-C210443 from LifeSpan Bioscience

Prices $515.00
Sizes 500 µl
Host Rabbit
Clonality Monoclonal
Clone SP230
Immunohistochemistry of Human mesothelioma stained with anti-tenascin X antibody

Anti-TNXB / Tenascin XB Antibody (clone 2D3-1B10) - LS-C139174 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D3-1B10
Western blot of TNXB expression in transfected 293T cell line by TNXB monoclonal antibody (M01), clone 2D3-1B10.

Tenascin X Antibody [Unconjugated] - AF6999 from Novus Biologicals

Prices $99.00, $369.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

Tenascin X Antibody (766842) [Unconjugated] - MAB6999 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 766842
Western blot shows lysates of human heart tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Tenascin X Monoclonal Antibody (Catalog # MAB6999) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Tenascin X at approximately 470 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Tenascin X Antibody (BC-24) - NB600-508 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone BC-24

Tenascin X Antibody (2D3-1B10) - H00007148-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2D3-1B10
Western Blot: Tenascin X Antibody (2D3-1B10) [H00007148-M01] - Analysis of TNXB expression in transfected 293T cell line by TNXB monoclonal antibody (M01), clone 2D3-1B10.Lane 1: TNXB transfected lysate (Predicted MW: 74 KDa).Lane 2: Non-transfected lysate.

Tenascin X Antibody (T2H5) - NB500-513 from Novus Biologicals

Prices $279.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone T2H5
Immunohistochemistry: Tenascin X Antibody (T2H5) [NB500-513] - Fig. 1. Immunohistochemistry staining of tonsil (paraffin-embedded sections) with anti-human Tenascin X Antibody (T2H5).

Tenascin X Antibody - H00007148-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Tenascin X Antibody [H00007148-B01P] - Analysis of TNXB expression in transfected 293T cell line by TNXB polyclonal antibody. Lane 1: TNXB transfected lysate(74.03 KDa). Lane 2: Non-transfected lysate.

Tenascin X Antibody - H00007148-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Tenascin X Antibody [H00007148-D01P] - Analysis of TNXB expression in transfected 293T cell line by TNXB polyclonal antibody.Lane 1: TNXB transfected lysate(74.00 KDa).Lane 2: Non-transfected lysate.

Anti-TNXB antibody produced in mouse - SAB1406543 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TNXB: <B>Cat. No. SAB1406543</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~74 kDa using TNXB transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-TNXB (166-180) antibody produced in rabbit - SAB1105801 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human TNXB was separated on SDS-PAGE, blotted with Anti-TNXB (166-180) (<B>Cat. No. SAB1105801</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-TNXB antibody produced in rabbit - SAB4502994 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TNXB: <B>Cat. No. SAB4502994</B>: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-TNXB antibody. Cells on the left were treated with the Anti-TNXB antibody. Cells on the right (negative control) were treated with both Anti-TNXB antibody and the synthesized immunogen peptide.

Anti-Tenascin X, Rabbit Monoclonal Antibody - SAB5500184 from Sigma-Aldrich

Prices $239.00
Sizes 100 µl
Clonality Monoclonal
Clone SP230
<B>Immunohistochemistry</B><BR/>Anti-Tenascin X: <B>Cat. No. SAB5500184</B>: Immunohistochemistry of Tenascin X in Human mesothelioma tissue with Tenascin X antibody.
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