Gene Symbol | Galnt1 |
---|---|
Entrez Gene | 14423 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1|galNAc-T1|polypeptide GalNAc transferase 1|polypeptide N-acetylgalactosaminyltransferase 1|pp-GaNTase 1|ppGaNTase-T1|protein-UDP acetylgalactosaminyltransferase 1 |
Swissprots | O08912 Q7TND1 Q5BKS3 |
Accessions | EDK96993 EDK96994 O08912 AK083391 AK085878 AK148550 BAE28617 BC038627 BC056215 AAH56215 BC090962 AAH90962 BY142456 BY711053 CX123572 U73820 AAB58477 XM_006525650 XP_006525713 NM_001160404 NP_001153876 NM_013814 NP_038842 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7. {ECO:0000269|PubMed:9153242}. |
Subcellular Location | Polypeptide N- acetylgalactosaminyltransferase 1: Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Widely expressed at high level. Higher expression in kidney, heart, small intestine and cervix and to a lesser extent in all the other tissues tested. {ECO:0000269|PubMed:12651884, ECO:0000269|PubMed:9153242}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 1(Galnt1) - CSB-YP009203MO CSB-EP009203MO CSB-BP009203MO CSB-MP009203MO from Cusabio
|
||||||||||
Polypeptide N-acetylgalactosaminyltransferase 1 (Galnt1), Recombinant Protein - MBS1193023 from MyBioSource
|
||||||||||
Recombinant Mouse GALNT1 Protein - GALNT1-6179M from Creative Biomart
|
||||||||||
Galnt1, 41-559aa, Mouse, His-tag, Baculovirus - ATGP3718 from ATGen
|
||||||||||
Polypeptide N-acetylgalactosaminyltransferase 1, Recombinant Protein - MBS7042782 from MyBioSource
|