SHC2

Gene Symbol SHC2
Entrez Gene 25759
Alt Symbol SCK, SHCB, SLI
Species Human
Gene Type protein-coding
Description SHC (Src homology 2 domain containing) transforming protein 2
Other Description SH2 domain protein C2|SHC-transforming protein 2|SHC-transforming protein B|neuronal Shc adaptor homolog|protein Sck|src homology 2 domain-containing-transforming protein C2
Swissprots Q9UCX4 Q9NPL5 O60230 P98077
Accessions P98077 AB001451 BAA25798 AL134433 AL360254 CAB96175 BC030527 BC034544 BC048290 BC156109 AAI56110 BC156898 AAI56899 BQ025513 BU754380 BY796046 CF457169 CK826553 XM_011527893 XP_011526195 XM_011527894 XP_011526196 XM_011527895 XP_011526197 XM_011527896 XP_011526198 NM_012435 NP_036567
Function Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus. {ECO:0000269|PubMed:9507002}.
Top Pathways Focal adhesion, Natural killer cell mediated cytotoxicity, Estrogen signaling pathway, Chronic myeloid leukemia, Prolactin signaling pathway

Sck CRISPR/Cas9 KO Plasmid (h) - sc-408568 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck HDR Plasmid (h) - sc-408568-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck Double Nickase Plasmid (h) - sc-408568-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck Double Nickase Plasmid (h2) - sc-408568-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck CRISPR Activation Plasmid (h) - sc-408568-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck CRISPR Activation Plasmid (h2) - sc-408568-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck Lentiviral Activation Particles (h) - sc-408568-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck Lentiviral Activation Particles (h2) - sc-408568-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sck siRNA (h) - sc-40928 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sck shRNA Plasmid (h) - sc-40928-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sck shRNA (h) Lentiviral Particles - sc-40928-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SHC2 RNAi - H00025759-R03 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

SHC2 RNAi - H00025759-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SHC2 RNAi - H00025759-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU118641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19291 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19291 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SHC2 siRNA (Human) - CRH8480 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHC2 - MBS8200388 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SHC2 (NM_012435.2) - SHH406976 from Creative biogene

Category siRNA
Species Reactivities Human

Human SHC2 siRNA - orb268982 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SHC2 shRNA Plasmid (Human) - CHH8480 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SHC2 miRNA 3'UTR clone - MiUTR3H-07482 from Creative biogene

Species Reactivities Human
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