TP73

Gene Symbol	TP73
Entrez Gene	7161
Alt Symbol	P73
Species	Human
Gene Type	protein-coding
Description	tumor protein p73
Other Description	p53-like transcription factor|p53-related protein
Swissprots	Q5TBV6 Q17RN8 O15351 Q8NHW9 O15350 B7Z8Z1 C9J521 B7Z9C1 B7Z7J4 Q5TBV5 Q9NTK8 Q8TDY6 Q8TDY5
Accessions	AAC61887 AAD39696 AAL38007 BAB87246 EAW71463 EAW71464 EAW71465 EAW71466 EAW71467 EAW71468 O15350 AB055065 BAB87244 AB055066 BAB87245 AI094238 AK295669 BAH12150 AK302118 BAH13630 AK304177 BAH14127 AK304784 BAH14257 AK310432 AY040827 AAK81884 AY040828 AAK81885 AY040829 AAK81886 BC117251 AAI17252 BC117253 AAI17254 DA439168 DA446656 DC345760 HQ258345 ADR83099 Y11416 CAA72219 XM_011542064 XP_011540366 NM_001126240 NP_001119712 NM_001126241 NP_001119713 NM_001126242 NP_001119714 NM_001204184 NP_001191113 NM_001204185 NP_001191114 NM_001204186 NP_001191115 NM_001204187 NP_001191116 NM_001204188 NP_001191117 NM_001204189 NP_001191118 NM_001204190 NP_001191119 NM_001204191 NP_001191120 NM_001204192 NP_001191121 NM_005427 NP_005418
Function	Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. {ECO:0000269|PubMed:10203277, ECO:0000269|PubMed:11753569, ECO:0000269|PubMed:18174154}.
Subcellular Location	Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage.
Tissue Specificity	Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue. {ECO:0000269|PubMed:11753569, ECO:0000269|PubMed:16461361}.
Top Pathways	p53 signaling pathway, Neurotrophin signaling pathway, Measles, Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-p73 Antibody, Affinity Purified - PLA0040 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Mouse/Human/Rat TP73 / p73 ELISA Kit (DNA-Binding ELISA) - LS-F903 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate

Mouse/Human Phospho-TP73 / p73 (Tyr99) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1599 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human TP73 / p73 ELISA Kit (Cell-Based ELISA) - LS-F2217 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

p73 Colorimetric Cell-Based ELISA Kit - CB5525 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

p73 (Phospho-Tyr99) Colorimetric Cell-Based ELISA Kit - CBP1653 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

p73 TFact™ DNA-Binding ELISA - TFE-7126 from Assay Biotechnology Category ELISA Kit Prices $495.00, $990.00, $1,485.00 Sizes 1 kit, 2 kits, 3 kits

tumor protein p73, ELISA Kit - MBS9323766 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0 pg/ml. Range 31.2 pg/ml - 1000 pg/ml.

p73 ELISA Kit - DEIA-XYA1392 from Creative Diagnostics Category ELISA Kit

p73 ELISA Kit - DEIA-XYA1393 from Creative Diagnostics Category ELISA Kit

p73 (Phospho-Tyr99) ELISA Kit - DEIA-XYA1394 from Creative Diagnostics Category ELISA Kit

Human TP73 ELISA Kit - E092696 from Biobool Category ELISA Kit

Tumor Protein P73 (TP73), ELISA Kit - MBS9370028 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9354192 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9344850 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9364349 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9356005 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9355520 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9352326 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9345394 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9347623 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9353154 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9365396 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9361200 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tumor Protein P73 (TP73), ELISA Kit - MBS9353033 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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