| Gene Symbol |
KDM3B
|
| Entrez Gene |
51780
|
| Alt Symbol |
5qNCA, C5orf7, JMJD1B, NET22
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lysine (K)-specific demethylase 3B
|
| Other Description |
jmjC domain-containing histone demethylation protein 2B|jumonji domain containing 1B|jumonji domain-containing protein 1B|lysine-specific demethylase 3B|nuclear protein 5qNCA
|
| Swissprots |
Q9NYF4 Q9BW93 A6H8X7 Q9BVH6 Q9UPS0 Q7LBC6 Q9BZ52
|
| Accessions |
EAW62141 EAW62142 Q7LBC6 AB029005 BAA83034 AF251039 AAF63765 AF338242 AAK13499 AK025755 AK304371 BAG65210 BC000539 AAH00539 BC001202 AAH01202 BC073869 BC117693 AAI17694 BC146788 AAI46789 BG390435 BI037147 BU149311 BU506660 BU752879 W28844 XM_005272018 XP_005272075 XM_011543488 XP_011541790 XM_011543489 XP_011541791 NM_016604 NP_057688
|
| Function |
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. {ECO:0000269|PubMed:16603237}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. {ECO:0000269|PubMed:11087669, ECO:0000269|PubMed:11687974}.
|