HYAL1

Gene Symbol	HYAL1
Entrez Gene	3373
Alt Symbol	HYAL-1, LUCA1, MPS9, NAT6
Species	Human
Gene Type	protein-coding
Description	hyaluronoglucosaminidase 1
Other Description	hyaluronidase-1|luCa-1|lung carcinoma protein 1|plasma hyaluronidase|tumor suppressor LUCA-1
Swissprots	Q8NFK6 Q12794 Q7KYU2 Q9UNI8 Q8NFK5 Q7LE34 Q93013 Q6FH23 Q9UKD5 Q8NFK8 Q6PIZ6 Q8NFK9 Q8NFK7
Accessions	AAB67046 AAC02730 EAW65083 EAW65084 EAW65085 EAW65086 EAW65087 EAW65088 EAW65089 EAW65090 EAW65091 Q12794 AF118821 AAD24460 AF173154 AAD53277 AF502904 AAM60770 AF502905 AAM60771 AF502906 AAM60772 AF502907 AAM60773 AF502908 AAM60774 AK097287 BAG53447 AK290816 BAF83505 BC025774 AAH25774 BC035695 AAH35695 CR541933 CAG46731 DA566755 DQ894083 ABM85009 EU176527 ABW03328 U03056 AAD09137 U96078 AAD04190 XM_011533667 XP_011531969 XM_011533668 XP_011531970 XM_011533669 XP_011531971 NM_033159 NP_149349 NM_153281 NP_695013 NM_153282 NP_695014 NM_153283 NP_695015 NM_153285 NP_695017 NR_047690 NM_153284 NM_153286
Function	May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. {ECO:0000269|PubMed:12084718}.
Subcellular Location	Secreted {ECO:0000269|PubMed:9223416}. Lysosome {ECO:0000269|PubMed:9223416}.
Tissue Specificity	Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues. {ECO:0000269|PubMed:10339581, ECO:0000269|PubMed:12084718, ECO:0000269|PubMed:9223416}.
Top Pathways	Lysosome, Glycosaminoglycan degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HYAL1 full length protein - ab112304 from Abcam Category Protein Source Wheat germ Species Human

Human HYAL1 protein fragment - ab112305 from Abcam Category Protein Source Wheat germ Species Human

HYAL1 peptide - ab107788 from Abcam Category Peptide

HYAL1 Antibody Blocking Peptide - LS-E3682 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HYAL1 Antibody Blocking Peptide - LS-E18350 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HYAL1 Antibody Blocking Peptide - LS-E18349 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HYAL1 Antibody Blocking Peptide - LS-E26381 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HYAL1 Antibody Blocking Peptide - LS-E26380 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAT6 / FUS2 Antibody Blocking Peptide - LS-E6308 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NAT6 / FUS2 Antibody Blocking Peptide - LS-E17620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Hyaluronidase 1/HYAL1 Protein - H00003373-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source Wheat Germ Species Human

Hyaluronidase 1/HYAL1 Partial Recombinant Protein - H00003373-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FUS2 Recombinant Protein - H00024142-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human FUS2 Protein - NBC1-21281 from Novus Biologicals Category Protein Prices $349.00 Sizes 10 µg Source E.coli Species Human

HYAL1-Antibody-C-term-Blocking-Peptide - BP14886b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HYAL1 blocking peptide - GTX89001-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

Recombinant Human Hyaluronidase 1/HYAL1, CF - 7358-GH-020 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met1-Trp435, with a C-terminal 6-His tag

Recombinant human Hyaluronidase-1 (OPCA01343) - OPCA01343 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

HYAL1 protein - orb90203 from Biorbyt Category Protein Prices $170.00, $289.00, $357.00 Sizes 1500 iu, 4500 iu, 15000 iu Source Bovine

Human HYAL1 protein - orb246158 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human HYAL1 protein - orb244824 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human NAT6 protein - orb90191 from Biorbyt Category Protein Prices $366.00, $417.00, $476.00 Sizes 2 μg, 10 μg, 5 μg Source E.coli Species Human

HYAL1 Blocking Peptide - 33R-9115 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HYAL1 Blocking Peptide - 33R-9982 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NAT6 Blocking Peptide - 33R-3683 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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