Gene Symbol | AFMID |
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Entrez Gene | 125061 |
Alt Symbol | FKF, KF, KFA |
Species | Human |
Gene Type | protein-coding |
Description | arylformamidase |
Other Description | FKF|KFA|KFase|N-formylkynurenine formamidase|kynurenine formamidase|probable arylformamidase |
Swissprots | Q63HM1 A2RUB3 |
Accessions | EAW89509 EAW89510 Q63HM1 BC020920 BC132824 AAI32825 BC142973 AAI42974 BX648442 CAH56149 EU832465 ACE87637 EU832546 ACE86948 HQ258157 ADR82911 XM_011524326 XP_011522628 XM_011524327 XP_011522629 XM_011524328 XP_011522630 XM_011524329 XP_011522631 XM_011524330 XP_011522632 XM_011524331 XP_011522633 XM_011524332 XP_011522634 XM_011524333 XP_011522635 XM_011524334 XP_011522636 XM_011524335 XP_011522637 XM_011524336 XP_011522638 XM_011524337 XP_011522639 XR_934369 NM_001010982 NP_001010982 NM_001145526 NP_001138998 NR_027083 |
Function | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. {ECO:0000255|HAMAP-Rule:MF_03014}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03014}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03014}. Note=Predominantly cytosolic. Some fraction is nuclear. {ECO:0000255|HAMAP-Rule:MF_03014}. |
Top Pathways | Glyoxylate and dicarboxylate metabolism, Tryptophan metabolism |
AFMID (S-15) - sc-163658 from Santa Cruz Biotechnology
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Anti-AFMID antibody - ab121870 from Abcam
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Anti-AFMID Antibody (aa57-83, AP) - LS-C250999 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83, Biotin) - LS-C251001 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83, APC) - LS-C251002 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83, FITC) - LS-C251003 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83, Azide-free, HRP) - LS-C251004 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83, PE) - LS-C251005 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa63-92) - LS-C319366 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa57-83) - LS-C156136 from LifeSpan Bioscience
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Anti-AFMID Antibody (aa3-36) - LS-C344691 from LifeSpan Bioscience
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AFMID Antibody - NBP1-94069 from Novus Biologicals
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AFMID Antibody - NBP1-94068 from Novus Biologicals
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Anti-AFMID antibody produced in rabbit - HPA026536 from Sigma-Aldrich
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Anti-AFMID antibody produced in rabbit - HPA023861 from Sigma-Aldrich
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AFMID-Antibody-N-term - AP9175a from Abgent, a WuXi AppTec company
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AFMID antibody, N-term - GTX80513 from GeneTex
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AFMID Antibody - N-terminal region (OAAB05766) - OAAB05766 from Aviva Systems Biology
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) - 031684 from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (AP) - 031684-AP from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (APC) - 031684-APC from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (Azide free)(HRP) - 031684-HRP from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (Biotin) - 031684-Biotin from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (FITC) - 031684-FITC from USBiological Life Science
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Anti -AFMID, NT (AFMID, Probable arylformamidase, Kynurenine formamidase) (PE) - 031684-PE from USBiological Life Science
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