| Gene Symbol |
WNT1
|
| Entrez Gene |
7471
|
| Alt Symbol |
BMND16, INT1, OI15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 1
|
| Other Description |
proto-oncogene Int-1 homolog|proto-oncogene Wnt-1|wingless-type MMTV integration site family, member 1 (oncogene INT1)
|
| Swissprots |
Q5U0N2 P04628
|
| Accessions |
CAA26874 CAI38639 EAW58030 P04628 BC074798 AAH74798 BC074799 AAH74799 BT019429 AAV38236 NM_005430 NP_005421
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development. {ECO:0000269|PubMed:23499309}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Top Pathways |
Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection
|
![Western Blot: Wnt1 Overexpression Lysate (Adult Normal) [NBL1-17860] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Wnt1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2600_Wnt1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17860-img0002.jpg)