Gene Symbol | WNT1 |
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Entrez Gene | 7471 |
Alt Symbol | BMND16, INT1, OI15 |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 1 |
Other Description | proto-oncogene Int-1 homolog|proto-oncogene Wnt-1|wingless-type MMTV integration site family, member 1 (oncogene INT1) |
Swissprots | Q5U0N2 P04628 |
Accessions | CAA26874 CAI38639 EAW58030 P04628 BC074798 AAH74798 BC074799 AAH74799 BT019429 AAV38236 NM_005430 NP_005421 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. Has a role in osteoblast function and bone development. {ECO:0000269|PubMed:23499309}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Active human Wnt1 full length protein - ab84080 from Abcam
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Active human Wnt1 full length protein - ab193878 from Abcam
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Human Wnt1 peptide - ab95923 from Abcam
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INT1 / INTS1 Antibody Blocking Peptide - LS-E1527 from LifeSpan Bioscience
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INT1 / INTS1 Antibody Blocking Peptide - LS-E24564 from LifeSpan Bioscience
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WNT1 Antibody Blocking Peptide - LS-E29439 from LifeSpan Bioscience
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WNT1 Antibody Blocking Peptide - LS-E11224 from LifeSpan Bioscience
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WNT1 Antibody Blocking Peptide - LS-E8456 from LifeSpan Bioscience
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WNT1 Antibody Blocking Peptide - LS-E29709 from LifeSpan Bioscience
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Recombinant Human Wnt-1 Protein - P4134 from Novus Biologicals
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Wnt-1 Protein - NBP1-99372 from Novus Biologicals
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Wnt-1 Protein - NBP1-99717 from Novus Biologicals
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WNT1-Antibody-C-term-Blocking-Peptide - BP6785b from Abgent, a WuXi AppTec company
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Wnt1 recombinant protein - GTX65282 from GeneTex
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Wnt1 recombinant protein - GTX65281 from GeneTex
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Wnt1 Recombinant Protein (Active) - GTX48341-PRO from GeneTex
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Human WNT-1 Protein (OPSA11032) - OPSA11032 from Aviva Systems Biology
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Wnt1 peptide - orb73349 from Biorbyt
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Wnt1 Blocking Peptide - 33R-10809 from Fitzgerald
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WNT1 Blocking Peptide - 33R-2912 from Fitzgerald
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Wnt1 protein - 30R-AW002 from Fitzgerald
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WNT1 protein - 30R-2697 from Fitzgerald
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WNT1 Blocking Peptide - abx063426 from Abbexa
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WNT1 - AR01023PU-N from Acris Antibodies
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WNT1 - AR01023PU-S from Acris Antibodies
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