RHOU

Gene Symbol	RHOU
Entrez Gene	58480
Alt Symbol	ARHU, CDC42L1, G28K, WRCH1, hG28K
Species	Human
Gene Type	protein-coding
Description	ras homolog family member U
Other Description	2310026M05Rik|CDC42-like GTPase 1|GTP-binding protein SB128|GTP-binding protein like 1|Ryu GTPase|ras homolog gene family, member U|ras-like gene family member U|rho GTPase-like protein ARHU|rho-related GTP-binding protein RhoU|wnt-1 responsive Cdc42 homolog 1
Swissprots	Q8TDQ2 Q59FE9 Q7L0Q8 B1AKN1
Accessions	ABD48870 ABD48871 ABD48872 ABD48873 ABD48874 ABD48875 CAY55989 CBX47521 EAW69885 EAW69886 Q7L0Q8 AB051826 BAB18638 AB074878 BAB86361 AB209511 BAD92748 AF211836 AAL54874 AF251701 AAL99390 AF282258 AAG46058 AF378087 AAK83340 AI094830 AK001478 AK289971 BAF82660 BC040076 AAH40076 DA321957 NM_021205 NP_067028 NR_037962
Function	Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP- bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. {ECO:0000269|PubMed:11459829, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058, ECO:0000269|PubMed:18086875, ECO:0000269|PubMed:21834987}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid- anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Cytoplasmic side {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Golgi apparatus membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid-anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell junction, focal adhesion {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell projection, podosome {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Note=Localizes to podosomes in SRC- transformed cells. {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}.
Tissue Specificity	Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta. {ECO:0000269|PubMed:11459829, ECO:0000269|PubMed:14731133}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WRCH1 peptide - ab23007 from Abcam Category Peptide Species Human

ARHU / RHOU Antibody Blocking Peptide - LS-E25326 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARHU / RHOU Antibody Blocking Peptide - LS-E15173 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ARHU / RHOU Antibody Blocking Peptide - LS-E15174 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WRCH1 blocking peptide - GTX89827-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

RHOU Immunizing peptide - orb17638 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

RHOU Blocking Peptide - 33R-5086 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

WRCH1 Peptide - AC21-0154-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

WRCH1 Peptide - 46-599P from ProSci Category Peptide

Recombinant Human Rho-related GTP-binding protein RhoU(RHOU) - CSB-YP745331HU CSB-EP745331HU CSB-BP745331HU CSB-MP745331HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ARHU/WRCH1, Peptide - MBS426017 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

WRCH1 Recombinant Protein Antigen - NBP2-13230PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RHOU Peptide, Human - M34GP13286H from Creative Peptides Category Peptide Source Synthetic. Species Human

RHOU fusion protein - Ag26498 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Rho-related GTP-binding protein RhoU (RHOU), Recombinant Protein - MBS1446891 from MyBioSource Category Protein Prices $1,010.00, $1,010.00, $1,240.00, $1,240.00, $1,550.00, $1,550.00, $2,015.00, $2,015.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

RHOU fusion protein - Ag26509 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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