RHOU

Gene Symbol	RHOU
Entrez Gene	58480
Alt Symbol	ARHU, CDC42L1, G28K, WRCH1, hG28K
Species	Human
Gene Type	protein-coding
Description	ras homolog family member U
Other Description	2310026M05Rik|CDC42-like GTPase 1|GTP-binding protein SB128|GTP-binding protein like 1|Ryu GTPase|ras homolog gene family, member U|ras-like gene family member U|rho GTPase-like protein ARHU|rho-related GTP-binding protein RhoU|wnt-1 responsive Cdc42 homolog 1
Swissprots	Q8TDQ2 Q59FE9 Q7L0Q8 B1AKN1
Accessions	ABD48870 ABD48871 ABD48872 ABD48873 ABD48874 ABD48875 CAY55989 CBX47521 EAW69885 EAW69886 Q7L0Q8 AB051826 BAB18638 AB074878 BAB86361 AB209511 BAD92748 AF211836 AAL54874 AF251701 AAL99390 AF282258 AAG46058 AF378087 AAK83340 AI094830 AK001478 AK289971 BAF82660 BC040076 AAH40076 DA321957 NM_021205 NP_067028 NR_037962
Function	Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP- bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. {ECO:0000269|PubMed:11459829, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058, ECO:0000269|PubMed:18086875, ECO:0000269|PubMed:21834987}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid- anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Cytoplasmic side {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Golgi apparatus membrane {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}; Lipid-anchor {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell junction, focal adhesion {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Cell projection, podosome {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}. Note=Localizes to podosomes in SRC- transformed cells. {ECO:0000269|PubMed:16046391, ECO:0000269|PubMed:16472646, ECO:0000269|PubMed:17620058}.
Tissue Specificity	Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta. {ECO:0000269|PubMed:11459829, ECO:0000269|PubMed:14731133}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WRCH1 (A-15) - sc-324492 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

WRCH1 (G-13) - sc-324491 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

WRCH1 (S-14) - sc-324490 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-WRCH1 antibody - ab80315 from Abcam Prices $370.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-WRCH1 antibody - N-terminal - ab189951 from Abcam Prices $407.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ARHU / RHOU Antibody (N-Terminus) - LS-C47028 from LifeSpan Bioscience Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ARHU / RHOU Antibody (aa2-16) - LS-C54532 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ARHU / RHOU Antibody (Internal) - LS-C94767 from LifeSpan Bioscience Prices $325.00 Sizes 500 µg Host Rabbit Clonality Polyclonal

Anti-ARHU / RHOU Antibody (aa41-90) - LS-C146086 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ARHU / RHOU Antibody IHC-plus™ - LS-B8900 from LifeSpan Bioscience Prices $395.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-ARHU / RHOU Antibody (C-Terminus) IHC-plus™ - LS-B5724 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

WRCH1 Antibody - NBP1-58350 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

WRCH1 Antibody - NBP1-20191 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

WRCH1 Antibody - NBP2-13230 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

WRCH1 Antibody - NB100-1007 from Novus Biologicals Prices $229.00 Sizes 100 µg Host Goat Clonality Polyclonal

WRCH1 Antibody - NBP1-33639 from Novus Biologicals Prices $279.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

WRCH-1 Polyclonal Antibody - bs-1944R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RHOU antibody produced in rabbit - AV41274 from Sigma-Aldrich Prices $316.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RHOU antibody - C-terminal region (ARP41274_P050) - ARP41274_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ARHU--WRCH1-Antibody-N-Term - AF2257a from Abgent, a WuXi AppTec company Prices $325.00 Sizes 100 µg Host Goat Clonality Polyclonal

ARHU / WRCH1 antibody, N-term - GTX89827 from GeneTex Prices $239.00 Sizes 100 μg Host Goat Clonality Polyclonal

Anti -ARHU (Rho-related GTP-binding Protein RhoU, CDC42-like GTPase 1, GTP-bindingProtein-like 1, Rho GTPase-like Protein ARHU, Ryu GTPase, Wnt-1 Responsive Cdc42 Homolog1, WRCH-1, RHOU, CDC42L1, G28K, WRCH1, SB128, DJ646B12.2, fJ646B12.2, FLJ10616) - 151158 from USBiological Life Science Host Goat Clonality Polyclonal

Goat Anti-ARHU / WRCH1 Antibody (OAEB00203) - OAEB00203 from Aviva Systems Biology Prices $229.00 Sizes 100 µg Host Goat Clonality Polyclonal

RHOU antibody - 70R-5757 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

WRCH-1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-1944R-A350 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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