Gene Symbol | RHOG |
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Entrez Gene | 391 |
Alt Symbol | ARHG |
Species | Human |
Gene Type | protein-coding |
Description | ras homolog family member G |
Other Description | ras homolog gene family, member G (rho G)|rho-related GTP-binding protein RhoG |
Swissprots | P35238 Q8NI04 P84095 |
Accessions | EAX02575 EAX02576 EAX02577 P84095 AA424888 AF498974 AAM21121 AY563952 AAS75333 BC104177 AAI04178 BC104178 AAI04179 BI196968 BT019872 AAV38675 BX359696 CB125569 CR450335 CAG29331 CR542105 CAG46902 L11317 AAA60268 X61587 CAA43784 XM_005252916 XP_005252973 NM_001665 NP_001656 |
Function | Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry. {ECO:0000269|PubMed:15133129, ECO:0000269|PubMed:17074883, ECO:0000269|PubMed:17875742, ECO:0000269|PubMed:20679435}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Bacterial invasion of epithelial cells, Salmonella infection |
Human RHOG full length protein - ab128454 from Abcam
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RHOG / ARHG Antibody Blocking Peptide - LS-E3983 from LifeSpan Bioscience
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RHOG / ARHG Antibody Blocking Peptide - LS-E22036 from LifeSpan Bioscience
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RhoG Recombinant Protein - H00000391-P01 from Novus Biologicals
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RhoG Partial Recombinant Protein - H00000391-Q01 from Novus Biologicals
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Recombinant Human RhoG Protein - NBP1-98934 from Novus Biologicals
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RHOG-Antibody-C-term-Blocking-Peptide - BP16200b from Abgent, a WuXi AppTec company
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Human RHOG protein - orb169195 from Biorbyt
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RHOG Blocking Peptide - 33R-5512 from Fitzgerald
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RhoG protein (His tag) - 80R-2335 from Fitzgerald
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RhoG (1-188, His-tag) - AR50419PU-N from Acris Antibodies
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RhoG (1-188, His-tag) - AR50419PU-S from Acris Antibodies
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RhoG - H00000391-P01 from Acris Antibodies
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RhoG - H00000391-Q01-10 from Acris Antibodies
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RhoG - H00000391-Q01-25 from Acris Antibodies
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RhoG, 1-188aa, Human, His tag, E.coli - 01-P1595 from ARP American Research Products
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RHOG Peptide - 7981P from ProSci
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RHOG fusion protein - ag16118 from Proteintech Group
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RHOG fusion protein - Ag17075 from Proteintech Group
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RHOG Human - PRPS-1143 from NeoScientific
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RhoG, 1-188aa, Recombinant Protein - GWB-P0443A from Genway Biotech
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Recombinant Human RHOG, His-tagged - RHOG-30980TH from Creative Biomart
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Recombinant Human Ras Homolog Family Member G, His-tagged - RHOG-6843H from Creative Biomart
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Rho G (Q132) Peptide - BS3931P from Bioworld Technology
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Recombinant Human Rho-related GTP-binding protein RhoG(RHOG) - CSB-YP019690HU CSB-EP019690HU CSB-BP019690HU CSB-MP019690HU from Cusabio
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