| Gene Symbol |
GP9
|
| Entrez Gene |
2815
|
| Alt Symbol |
CD42a, GPIX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycoprotein IX (platelet)
|
| Other Description |
glycoprotein 9|platelet glycoprotein IX
|
| Swissprots |
Q8N1D1 P14770 Q14445 Q92525
|
| Accessions |
AAB40042 AAD14929 ACZ44928 BAA13580 BAA24428 CBX54457 CDI44164 EAW79285 P14770 AA701315 BC030229 AAH30229 BM971739 DQ893337 ABM84263 DQ896655 ABM87654 M25827 AAA36809 X52997 CAA37186 XM_005247374 XP_005247431 XM_011512701 XP_011511003 XM_011512702 XP_011511004 NM_000174 NP_000165
|
| Function |
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
ECM-receptor interaction, Hematopoietic cell lineage
|
