Gene Symbol | GP9 |
---|---|
Entrez Gene | 2815 |
Alt Symbol | CD42a, GPIX |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein IX (platelet) |
Other Description | glycoprotein 9|platelet glycoprotein IX |
Swissprots | Q8N1D1 P14770 Q14445 Q92525 |
Accessions | AAB40042 AAD14929 ACZ44928 BAA13580 BAA24428 CBX54457 CDI44164 EAW79285 P14770 AA701315 BC030229 AAH30229 BM971739 DQ893337 ABM84263 DQ896655 ABM87654 M25827 AAA36809 X52997 CAA37186 XM_005247374 XP_005247431 XM_011512701 XP_011511003 XM_011512702 XP_011511004 NM_000174 NP_000165 |
Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |