Gene Symbol | GP9 |
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Entrez Gene | 2815 |
Alt Symbol | CD42a, GPIX |
Species | Human |
Gene Type | protein-coding |
Description | glycoprotein IX (platelet) |
Other Description | glycoprotein 9|platelet glycoprotein IX |
Swissprots | Q8N1D1 P14770 Q14445 Q92525 |
Accessions | AAB40042 AAD14929 ACZ44928 BAA13580 BAA24428 CBX54457 CDI44164 EAW79285 P14770 AA701315 BC030229 AAH30229 BM971739 DQ893337 ABM84263 DQ896655 ABM87654 M25827 AAA36809 X52997 CAA37186 XM_005247374 XP_005247431 XM_011512701 XP_011511003 XM_011512702 XP_011511004 NM_000174 NP_000165 |
Function | The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
CD42a CRISPR/Cas9 KO Plasmid (h) - sc-405500 from Santa Cruz Biotechnology
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CD42a HDR Plasmid (h) - sc-405500-HDR from Santa Cruz Biotechnology
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CD42a Double Nickase Plasmid (h) - sc-405500-NIC from Santa Cruz Biotechnology
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CD42a Double Nickase Plasmid (h2) - sc-405500-NIC-2 from Santa Cruz Biotechnology
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CD42a CRISPR Activation Plasmid (h) - sc-405500-ACT from Santa Cruz Biotechnology
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CD42a CRISPR Activation Plasmid (h2) - sc-405500-ACT-2 from Santa Cruz Biotechnology
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CD42a Lentiviral Activation Particles (h) - sc-405500-LAC from Santa Cruz Biotechnology
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CD42a Lentiviral Activation Particles (h2) - sc-405500-LAC-2 from Santa Cruz Biotechnology
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CD42a siRNA (h) - sc-42787 from Santa Cruz Biotechnology
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CD42a shRNA Plasmid (h) - sc-42787-SH from Santa Cruz Biotechnology
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CD42a shRNA (h) Lentiviral Particles - sc-42787-V from Santa Cruz Biotechnology
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GP-IX RNAi - H00002815-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9499 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9499 from Sigma-Aldrich
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GP9 siRNA (Human) - CRH1882 from Cohesion Biosciences
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GP9 - MBS8214332 from MyBioSource
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shRNA set against Human GP9 (NM_000174.3) - SHH305578 from Creative biogene
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Human GP9 siRNA - orb262384 from Biorbyt
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GP9 shRNA Plasmid (Human) - CHH1882 from Cohesion Biosciences
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