Gene Symbol | FABP6 |
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Entrez Gene | 2172 |
Alt Symbol | I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP |
Species | Human |
Gene Type | protein-coding |
Description | fatty acid binding protein 6, ileal |
Other Description | GT|gastrotropin|ileal bile acid binding protein|ileal lipid-binding protein|illeal lipid-binding protein|intestinal 15 kDa protein |
Swissprots | P51161 Q8TBI3 Q07DR7 Q9UGI7 |
Accessions | CAB65728 CAC81780 EAW61563 EAW61564 EAW61565 EAW61566 P51161 AI208231 BC022489 AAH22489 DQ132786 ABA12611 HQ448339 ADQ32819 U19869 AAB82751 X90908 CAA62415 XM_006714830 XP_006714893 XM_011534463 XP_011532765 NM_001040442 NP_001035532 NM_001130958 NP_001124430 NM_001445 NP_001436 |
Function | Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis. {ECO:0000269|PubMed:17909007}. |
Subcellular Location | Isoform 1: Cytoplasm. |
Tissue Specificity | Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. {ECO:0000269|PubMed:17909007}. |
Top Pathways | PPAR signaling pathway |
ILBP (C-20) - sc-23994 from Santa Cruz Biotechnology
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ILBP (FL-128) - sc-366668 from Santa Cruz Biotechnology
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ILBP (N-20) - sc-23992 from Santa Cruz Biotechnology
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Anti-FABP6 antibody - ab96122 from Abcam
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Anti-FABP6 antibody - ab67070 from Abcam
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Anti-FABP6 antibody - N-terminal - ab191301 from Abcam
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Anti-I-BABP / FABP6 Antibody - LS-C140219 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (aa1-128, Biotin) - LS-C297300 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (aa1-128, FITC) - LS-C303091 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody - LS-C307955 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody - LS-C310310 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (aa1-128) - LS-C293837 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody - LS-C334969 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (aa1-142) IHC-plus⢠- LS-B10818 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (clone 4A4) - LS-C197187 from LifeSpan Bioscience
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Anti-I-BABP / FABP6 Antibody (aa15-33) - LS-C313262 from LifeSpan Bioscience
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FABP6 Antibody [Unconjugated] - AF3880 from Novus Biologicals
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FABP6 Antibody - NBP1-83129 from Novus Biologicals
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FABP6 Antibody - NBP1-32482 from Novus Biologicals
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FABP6 Antibody (4A4) - H00002172-M01 from Novus Biologicals
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FABP6 Antibody - H00002172-B01P from Novus Biologicals
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FABP6 Antibody - H00002172-B01 from Novus Biologicals
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FABP6 Antibody - H00002172-D01P from Novus Biologicals
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FABP6 Antibody [Biotin] - BAF3880 from Novus Biologicals
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Anti-FABP6 antibody produced in rabbit - HPA012601 from Sigma-Aldrich
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