Gene Symbol | CDCA5 |
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Entrez Gene | 113130 |
Alt Symbol | SORORIN |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle associated 5 |
Other Description | cell division cycle-associated protein 5|p35|sororin |
Swissprots | A8K625 Q96FF9 |
Accessions | EAW74342 EAW74343 Q96FF9 AK093670 BAG52747 AK291490 BAF84179 AL832526 BC011000 AAH11000 CN332525 DQ893251 ABM84177 DQ896580 ABM87579 XM_005273733 XP_005273790 XM_005273734 XP_005273791 XM_011544743 XP_011543045 XM_011544744 XP_011543046 XM_011544745 XP_011543047 XM_011544746 XP_011543048 XM_011544747 XP_011543049 XM_011544748 XP_011543050 XM_011544749 XP_011543051 XR_949779 XR_949781 NM_080668 NP_542399 |
Function | Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair. {ECO:0000269|PubMed:15837422, ECO:0000269|PubMed:17349791, ECO:0000269|PubMed:21111234}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15837422}. Chromosome {ECO:0000269|PubMed:15837422}. Cytoplasm {ECO:0000269|PubMed:15837422}. Note=Associates with nuclear chromatin from S phase until metaphase and is released in the cytoplasm upon nuclear envelope breakdown. |
Top Pathways | MicroRNAs in cancer |
Human CDCA5 full length protein - ab164993 from Abcam
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CDCA5 / Sororin Antibody Blocking Peptide - LS-E21316 from LifeSpan Bioscience
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Recombinant Human CDCA5 Protein - H00113130-P01 from Novus Biologicals
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CDCA5 Blocking Peptide - 33R-1570 from Fitzgerald
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CDCA5 Blocking Peptide - 33R-8165 from Fitzgerald
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p35 Blocking Peptide - abx063527 from Abbexa
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CDCA5 / Sororin - H00113130-P01-10 from Acris Antibodies
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CDCA5 / Sororin - H00113130-P01-25 from Acris Antibodies
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CDCA5 fusion protein - ag1414 from Proteintech Group
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Recombinant Interleukin 12A (IL12A) - RPA059Hu01 from Cloud-clone
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Recombinant Human Sororin(CDCA5) - CSB-YP822211HU CSB-EP822211HU CSB-BP822211HU CSB-MP822211HU from Cusabio
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CCDC5 Protein - abx164991 from Abbexa
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CDCA5 Recombinant Protein Antigen - NBP1-89530PEP from Novus Biologicals
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CDCA5 Antibody - SH-A10958 from Novatein Biosciences
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CDCA5 Peptide, Human - M34GP02823H from Creative Peptides
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Protein P35 (XXXV), Recombinant Protein - MBS7033688 from MyBioSource
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Sororin (CDCA5), Recombinant Protein - MBS1438217 from MyBioSource
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