| Gene Symbol |
ISCA1
|
| Entrez Gene |
81689
|
| Alt Symbol |
HBLD2, ISA1, hIscA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
iron-sulfur cluster assembly 1
|
| Other Description |
HESB like domain containing 2|HESB-like domain-containing protein 2|iron sulfur assembly protein IscA|iron-sulfur assembly protein IscA|iron-sulfur cluster assembly 1 homolog, mitochondrial
|
| Swissprots |
Q9BZR2 B4DJI5 Q8ND75 B3KP34 Q9BUE6
|
| Accessions |
EAW62712 EAW62713 Q9BUE6 AA745613 AF038186 AF284752 AAG59854 AI436792 AK055643 BAG51546 AK225937 AK296093 BAG58847 AL834356 CAD39021 AY015642 AAG40950 BC002675 AAH02675 BC053900 BC071621 AAH71621 BG772866 NM_030940 NP_112202
|
| Function |
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. {ECO:0000269|PubMed:15262227, ECO:0000269|PubMed:22323289}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:15262227, ECO:0000269|PubMed:22323289}.
|
| Tissue Specificity |
Detected in cerebellum, kidney and heart. {ECO:0000269|PubMed:15262227}.
|
![Western Blot: HBLD2 Overexpression Lysate (Adult Normal) [NBL1-12043] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HBLD2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7886_HBLD2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12043-img0002.jpg)