COPA

Gene Symbol	COPA
Entrez Gene	1314
Alt Symbol	HEP-COP
Species	Human
Gene Type	protein-coding
Description	coatomer protein complex, subunit alpha
Other Description	HEPCOP|alpha coat protein|alpha-COP|alpha-coat protein|coatomer subunit alpha|proxenin|xenin
Swissprots	P53621 Q8IXZ9 Q5T201
Accessions	CAH56812 EAW52723 EAW52724 EAW52725 P53621 AK129830 AK307953 BC037941 BC038447 AAH38447 DC308331 U24105 AAB70879 NM_001098398 NP_001091868 NM_004371 NP_004362
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.
Tissue Specificity	Uniformly expressed in a wide range of adult and fetal tissues. Xenin is found in gastric, duodenal and jejunal mucosa. Circulates in the blood. Seems to be confined to specific endocrine cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

alpha COP I peptide - ab4931 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human alpha COP I protein fragment - ab152291 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

COPA / Xenin Antibody Blocking Peptide - LS-E27535 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COPA / Xenin Antibody Blocking Peptide - LS-E18618 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COPA / Xenin Antibody Blocking Peptide - LS-E18619 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human alpha COP I Protein - H00001314-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Xenin - SP2956b from Abgent, a WuXi AppTec company Category Peptide Prices $165.00 Sizes 1 mg

Xenin - SP2956a from Abgent, a WuXi AppTec company Category Peptide Prices $125.00 Sizes 500 µg

Xenin peptide - orb72042 from Biorbyt Category Peptide Prices $536.00 Sizes 5 mg

COPA Blocking Peptide - 33R-7432 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

COPA Blocking Peptide - 33R-4092 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Xenin Peptide - abx064775 from Abbexa Category Peptide

Alpha COP I Peptide - AC21-2357-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Coatomer subunit alpha (COPA) - H00001314-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Coatomer subunit alpha (COPA) - H00001314-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Coatomer subunit alpha (COPA) Control Peptide - SP5145CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Xenin - 55227 from NeoScientific Category Peptide Prices $69.00, $345.00 Sizes 1 mg, 10 mg

Xenin Peptide - 350429 from ABBIOTEC Category Peptide Prices $226.00 Sizes 1 mg

Xenin - GWB-B04993 from Genway Biotech Category Peptide Prices $150.00, $270.00 Sizes 500 µg, 1 mg

Xenin - CCP1476 from Cohesion Biosciences Category Peptide Prices $138.00, $414.00, $690.00 Sizes 1 mg, 5 mg, 10 mg

Recombinant Human Coatomer subunit alpha(COPA) ,partial - CSB-YP005782HU CSB-EP005782HU CSB-BP005782HU CSB-MP005782HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

COPA, Peptide - MBS427990 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine, Pig

Xenin, Peptide - MBS826427 from MyBioSource Category Peptide Prices $205.00, $460.00, $725.00 Sizes 1 mg, 5 mg, 10 mg Source Synthetic

alpha COP I Recombinant Protein Antigen - NBP1-89705PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Xenin - abx266908 from Abbexa

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