Gene Symbol | PPP2CB |
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Entrez Gene | 5516 |
Alt Symbol | PP2Abeta, PP2CB |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, catalytic subunit, beta isozyme |
Other Description | PP2A-beta|protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform|protein phosphatase 2, catalytic subunit, beta isoform|protein phosphatase 2A catalytic subunit, beta isoform|protein phosphatase type 2A catalytic subunit|serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform|serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
Swissprots | Q6FHK5 P11082 D3DSV4 P62714 |
Accessions | AAA36467 EAW63433 EAW63434 EAW63435 EAW63436 P62714 AF444006 AAL35904 AK091875 BAG52434 BC012022 AAH12022 BG716837 BT019526 AAV38333 CA419001 CF594136 CR541747 CAG46547 J03805 AAB38020 X12656 CAA31183 NM_001009552 NP_001009552 NM_004156 |
Function | PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. {ECO:0000269|PubMed:2555176}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16541025}. Nucleus {ECO:0000269|PubMed:16541025}. Chromosome, centromere {ECO:0000269|PubMed:16541025}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16541025}. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. |
Top Pathways | Sphingolipid signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway, Hippo signaling pathway, TGF-beta signaling pathway |
Human PPP2CB full length protein - ab128562 from Abcam
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Human PPP2CB full length protein - ab114425 from Abcam
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PP2CB / PPP2CB Antibody Blocking Peptide - LS-E2687 from LifeSpan Bioscience
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Recombinant Human PPP2CB Protein - H00005516-P01 from Novus Biologicals
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PPP2CB-Antibody-C-term-Blocking-peptide - BP13765b from Abgent, a WuXi AppTec company
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Human PPP2CB protein - orb245058 from Biorbyt
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PPP2CB - H00005516-P01-10 from Acris Antibodies
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PPP2CB - H00005516-P01-25 from Acris Antibodies
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PPP2CB fusion protein - ag3233 from Proteintech Group
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Recombinant Human PPP2CB - PPP2CB-27931TH from Creative Biomart
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PP2A beta protein-GST fusion - 009-001-T01 from Rockland Immunochemicals Inc
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PP2A beta protein-GST fusion - 009-001-T01S from Rockland Immunochemicals Inc
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Recombinant human Serine/threonine-protein phosphatase 2A catalytic subunit beta - CSB-EP009854h CSB-BP009854h CSB-MP009854h from Cusabio
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Recombinant Human Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform(PPP2CB) - CSB-RP009854h from Cusabio
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Recombinant Human Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform(PPP2CB) - CSB-YP018560HU CSB-EP018560HU CSB-BP018560HU CSB-MP018560HU from Cusabio
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PPP2CB (full length, N-term HIS tag) - TP760699 from Acris Antibodies
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PP2Abeta, Recombinant Protein - MBS515214 from MyBioSource
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PPP2CB Peptide, Human - M34GP12269H from Creative Peptides
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Recombinant human Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform - AP71691 from Signalway Antibody
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Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, Recombinant Protein - MBS717223 from MyBioSource
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Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, Recombinant Protein - MBS9421546 from MyBioSource
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Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB), Recombinant Protein - MBS958223 from MyBioSource
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Recombinant Human PPP2CB Protein (1-309 aa), GST-tagged - PPP2CB-1178H from Creative Biomart
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