Gene Symbol | PPP2CB |
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Entrez Gene | 5516 |
Alt Symbol | PP2Abeta, PP2CB |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, catalytic subunit, beta isozyme |
Other Description | PP2A-beta|protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform|protein phosphatase 2, catalytic subunit, beta isoform|protein phosphatase 2A catalytic subunit, beta isoform|protein phosphatase type 2A catalytic subunit|serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform|serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
Swissprots | Q6FHK5 P11082 D3DSV4 P62714 |
Accessions | AAA36467 EAW63433 EAW63434 EAW63435 EAW63436 P62714 AF444006 AAL35904 AK091875 BAG52434 BC012022 AAH12022 BG716837 BT019526 AAV38333 CA419001 CF594136 CR541747 CAG46547 J03805 AAB38020 X12656 CAA31183 NM_001009552 NP_001009552 NM_004156 |
Function | PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. {ECO:0000269|PubMed:2555176}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16541025}. Nucleus {ECO:0000269|PubMed:16541025}. Chromosome, centromere {ECO:0000269|PubMed:16541025}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16541025}. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. |
Top Pathways | Sphingolipid signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway, Hippo signaling pathway, TGF-beta signaling pathway |
demethylated-PP2A-C (4i57) - sc-80990 from Santa Cruz Biotechnology
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Anti-PPP2CB antibody - ab198926 from Abcam
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Anti-PPP2CB antibody - ab154542 from Abcam
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Anti-PPP2CB antibody - ab72450 from Abcam
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Anti-PPP2CB antibody - ab116324 from Abcam
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Anti-PPP2CB antibody [EPR11786(B)] - ab168371 from Abcam
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Anti-PPP2CB antibody [EPR11787(B)] - ab168350 from Abcam
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Anti-PP2CB / PPP2CB Antibody (aa295-309) - LS-C38583 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa295-309, clone 1D6) - LS-C38584 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa290-304) - LS-C38588 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (C-Terminus) - LS-C91573 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody - LS-C91574 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (C-Terminus) - LS-C91575 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa302-309) - LS-C126184 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa21-31) - LS-C131251 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody - LS-C131258 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (Biotin) - LS-C183249 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (FITC) - LS-C183250 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody - LS-C190012 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (HRP) - LS-C183251 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa278-307, PE) - LS-C284724 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa278-307, APC) - LS-C284723 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa278-307, AP) - LS-C284725 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (aa1-50) - LS-C287596 from LifeSpan Bioscience
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Anti-PP2CB / PPP2CB Antibody (C-Terminus) - LS-C287597 from LifeSpan Bioscience
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