| Gene Symbol | XRCC1 |
|---|---|
| Entrez Gene | 7515 |
| Alt Symbol | RCC |
| Species | Human |
| Gene Type | protein-coding |
| Description | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| Other Description | DNA repair protein XRCC1|X-ray repair cross-complementing protein 1 |
| Swissprots | Q9HCB1 Q6IBS4 P18887 |
| Accessions | AAG09061 AAM34791 AGB76026 AGI15891 AGI15892 AGI15893 AHC92541 EAW57201 EAW57202 EAW57203 P18887 AB208781 BAD92018 AK293542 BAG57023 AK300163 BAG61945 AK315332 BAG37732 BC023593 AAH23593 BP349667 CR456728 CAG33009 M36089 AAA63270 NM_006297 NP_006288 |
| Function | Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:17353262}. Note=Accumulates at sites of DNA damage. |
| Top Pathways | Base excision repair |