| Gene Symbol |
XRCC1
|
| Entrez Gene |
7515
|
| Alt Symbol |
RCC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
X-ray repair complementing defective repair in Chinese hamster cells 1
|
| Other Description |
DNA repair protein XRCC1|X-ray repair cross-complementing protein 1
|
| Swissprots |
Q9HCB1 Q6IBS4 P18887
|
| Accessions |
AAG09061 AAM34791 AGB76026 AGI15891 AGI15892 AGI15893 AHC92541 EAW57201 EAW57202 EAW57203 P18887 AB208781 BAD92018 AK293542 BAG57023 AK300163 BAG61945 AK315332 BAG37732 BC023593 AAH23593 BP349667 CR456728 CAG33009 M36089 AAA63270 NM_006297 NP_006288
|
| Function |
Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:17353262}. Note=Accumulates at sites of DNA damage.
|
| Top Pathways |
Base excision repair
|