XRCC1

Gene Symbol XRCC1
Entrez Gene 7515
Alt Symbol RCC
Species Human
Gene Type protein-coding
Description X-ray repair complementing defective repair in Chinese hamster cells 1
Other Description DNA repair protein XRCC1|X-ray repair cross-complementing protein 1
Swissprots Q9HCB1 Q6IBS4 P18887
Accessions AAG09061 AAM34791 AGB76026 AGI15891 AGI15892 AGI15893 AHC92541 EAW57201 EAW57202 EAW57203 P18887 AB208781 BAD92018 AK293542 BAG57023 AK300163 BAG61945 AK315332 BAG37732 BC023593 AAH23593 BP349667 CR456728 CAG33009 M36089 AAA63270 NM_006297 NP_006288
Function Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
Subcellular Location Nucleus {ECO:0000269|PubMed:17353262}. Note=Accumulates at sites of DNA damage.
Top Pathways Base excision repair

XRCC1 Antibody - 2735 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Jurkat and K562 cells using XRCC1 Antibody.

XRCC1 (H-300) - sc-11429 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
XRCC1 (H-300): sc-11429. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse lung tissue showing nuclear localization.

XRCC1 (D-18) - sc-5902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XRCC1 (D-18): sc-5902. Western blot analysis of XRCC1 expression in non-transfected: sc-117752 (A) and mouse XRCC1 transfected: sc-127792 (B) 293T whole cell lysates.

XRCC1 (C-15) - sc-5903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XRCC1 (C-15): sc-5903. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing nuclear and cytoplasmic staining of cells in glomeruli and cells in tubules.

XRCC1 (33-2-5) - sc-56254 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
XRCC1 (33-2-5): sc-56254. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing nuclear localization.

Anti-XRCC1 (phospho S461) antibody - ab84413 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of two serial sections of formalin-fixed, paraffin-embedded Human breast adenocarcinoma, using 1/250 ab84413 followed by DAB staining. Left panel: mock phosphatase treated; Right panel: calf intestinal phosphatase-treated.

Anti-XRCC1 (phospho S518 + T519 + T523) antibody - ab84417 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human XRCC1 (phospho S518 + T519 + T523) by Immunohistochemistry.Samples: FFPE serial sections of Human breast adenocarcinoma. Mock phosphatase treated section (left) or calf intestinal phosphatase-treated section (right) immunostained for XRCC1 (phospho S518 + T519 + T523).Antibody: ab84417 used at a dilution of 1/250.Detection: DAB staining.

Anti-XRCC1 (phospho S518 + T519 + T523) antibody - ab195205 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-XRCC1 antibody - ab155043 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-XRCC1 antibody (ab155043) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-XRCC1 antibody - ab58465 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-XRCC1 antibody (ab58465) at 1/500 dilutionLane 1 : Extracts from Jurkat cellsLane 2 : Extracts from Jurkat cells with immunizing peptide

Anti-XRCC1 antibody [33-2-5] - ab1838 from Abcam

Prices $403.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 33-2-5
ab1838 - immunohistochemistry Formalin fixed paraffin embedded human testis stained with XRCC1, using ABC and AEC chromogen.

Anti-XRCC1 antibody [33-2-5] (Biotin) - ab79219 from Abcam

Prices $373.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 33-2-5

Anti-XRCC1 antibody [EPR4389(2)] - ab134056 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4389(2)
All lanes : Anti-XRCC1 antibody [EPR4389(2)] (ab134056) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A375 cell lysateLane 3 : Saos-2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-XRCC1 antibody [EPR4389(2)] (HRP) - ab198549 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4389(2)
Anti-XRCC1 antibody [EPR4389(2)] (HRP) (ab198549) at 1/5000 dilution + Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-XRCC1 antibody [SPM327], prediluted - ab54393 from Abcam

Prices $378.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM327
ab54393 (prediluted) staining XRCC1 in human testis by Immunohistochemistry, Formalin-fixed, Paraffin embedded tissue.

Anti-XRCC1 Antibody (Gly552) - LS-C176370 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of XRCC1 (G552) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-XRCC1 Antibody (Internal, clone EPR4389(2)) - LS-C138405 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4389(2)
IHC of paraffin-embedded human testis tissue using anti-XRCC1 antibody.

Anti-XRCC1 Antibody (aa414-443) - LS-C326398 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XRCC1 Antibody (phospho-Ser461) - LS-C287078 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Phospho XRCC1 (S461) by Immunohistochemistry. Samples: FFPE serial sections of human larynx squamous cell carcinoma. Mock phosphatase treated section (left) and calf intestinal phosphatase-treated section (right). Antibody: Affinity purified rabbit anti-Phospho XRCC1 (S461). used at a dilution of 1:1000 (1 ug/ml. Detection: DAB.

Anti-XRCC1 Antibody (C-Terminus) - LS-C287006 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human XRCC1 by Western Blot. Sample: Whole cell extract (50 ug) from mock treated or siRNA treated HeLa cells. Antibody: Affinity purified rabbit anti-XRCC1 used at 1 ug/ml. Detection: Chemiluminescence.

Anti-XRCC1 Antibody (phospho-Ser518) - LS-C287001 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Phospho-ERCC1 (S518/T519/T523) by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-Phospho-XRCC1 (S518/T519/T523) used at a dilution of 1:5000 (0.2 Detection: DAB.

Anti-XRCC1 Antibody (phospho-Ser485) - LS-C286387 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse Phospho XRCC1 (S485/T488) by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-Phospho XRCC1 (S485/T488). used at a dilution of 1:250.

Anti-XRCC1 Antibody - LS-C330961 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of A375 cell lines, using XRCC1 antibody.

Anti-XRCC1 Antibody (aa407-435) - LS-C160670 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
XRCC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skin carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-XRCC1 Antibody (phospho-Ser461) - LS-C286389 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse Phospho XRCC1 (S461) by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-Phospho XRCC1 (S461). used at a dilution of 1:250.
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